Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 670 clinical trials
Neurology Measures in FA Children

The purpose of this study is to identify ways to follow progression of Friedreich's Ataxia (FA) and be able to measure changes over time in children with FA. Participants will have biannual visits to observe how the disease progresses over time and determine the rate of progression. Funding Source- Food …

genetic testing
  • 55 views
  • 24 Jan, 2021
  • 3 locations
rTMS in Treatment of Spasticity

This is an open-label clinical trial to determine the safety and efficacy of rTMS in reducing spasticity and improving quality of life among patients with upper motor neuron predominant motor neuron disease (MND).

riluzole
spasticity
motor neuron disease
edaravone
primary lateral sclerosis
  • 6 views
  • 26 Jan, 2021
  • 1 location
Biomarker for Friedreich's Ataxia (BioFridA)

International, multicenter, observational, longitudinal monitoring study to identify biomarker/s for Friedreich's Ataxia and to explore the clinical robustness, specificity, and long-term variability of these biomarker/s

  • 0 views
  • 25 Jan, 2021
  • 1 location
Assessment of Poliovirus Type 2 Immunogenicity of One and Two Dose Schedule With IPV and fIPV When Administered at 9-13 Months of Age in Bangladesh

Following a recommendation on October 2017 meeting of the Strategic Advisory Group of Experts (SAGE) on Immunization; low- risk bOPV-using countries may adopt 2 dose fIPV schedule prior to global OPV cessation as it provides better seroconversion than 1 full dose IPV and in the post-cessation era, the 2 fIPV …

bleeding disorder
severe malnutrition
malnutrition
routine immunization
  • 2 views
  • 20 Feb, 2021
  • 2 locations
Remote Pulmonary Function Testing and Nurse Coaching in ALS

Comparison of respiratory outcomes in patients receiving telemedicine-guided remote pulmonary function testing (rPFT) with or without the additional support of nurse coaching. This is a randomized controlled study which assesses the effects rPFT and coaching on respiratory outcomes and quality of life.

pulmonary function test
  • 0 views
  • 25 Jan, 2021
  • 1 location
Multiple Ascending Dose Study of CTI-1601 Versus Placebo in Subjects With Friedreich's Ataxia

To evaluate the safety and tolerability of multiple ascending doses of CTI-1601 in participants with Friedreich's ataxia

  • 5 views
  • 24 Jan, 2021
  • 1 location
Effect of Lactoferrin on Polio Seroconversion

A massive decline in cases of poliomyelitis was observed worldwide since 1988; however its transmission continues in Pakistan and Afghanistan. In 2017, a total of 17 cases were reported from these countries, which represent approximately half of the cases reported in 2016. This achievement was made possible by large scale …

poliomyelitis vaccine
malnutrition
inactivated poliovirus vaccine
bovine lactoferrin
5 minutes
  • 0 views
  • 25 Jan, 2021
  • 1 location
Amyotrophic Lateral Sclerosis (ALS) Families Project

This program provides family members of individuals with familial ALS the opportunity to contribute to research focused on learning more about why motor neuron degeneration begins and how or why it progresses. This study provides genetic counseling and testing to help participants understand and manage their risk and determine if …

motor neuron degeneration
dementia
genetic testing
primary lateral sclerosis
  • 0 views
  • 26 Jan, 2021
Safety and Efficacy of Etravirine in Friedreich Ataxia Patients

A drug repositioning effort provided evidence supporting the possible use of Etravirine, a drug approved for the treatment of HIV infections in patients starting from 2 years of age, as a treatment for FA. We found that Etravirine is able to increase Frataxin protein both in vitro - in cells …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Clinical Trial of Novel OPV2 Vaccine

Though OPV is safe and effective, it can mutate and reacquire neurovirulence in rare circumstances. This can result in vaccine-associated paralytic polio and circulating vaccine-derived polioviruses. Use of tOPV had risk of generating VAPP and seeding new type 2 circulating vaccine-derived polioviruses though wild type 2 virus was eradicated in …

  • 0 views
  • 27 Jan, 2021
  • 1 location