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Found 670 clinical trials
Adjuvant Whole Abdominal Intensity Modulated Radiotherapy (IMRT) for High Risk Stage FIGO III Patients With Ovarian Cancer

The prognosis for patients with advanced epithelial ovarian cancer remains poor despite aggressive surgical resection and platinum-based chemotherapy. More than 60% of patients will develop recurrent disease, principally intraperitoneal, and die within 5 years. The use of whole abdominal irradiation (WAI) as consolidation therapy would appear to be a logical …

paclitaxel
residual tumor
recurrent disease
immunostimulant
platinum-based chemotherapy
  • 46 views
  • 07 Nov, 2020
  • 1 location
The Impact of an Epidural Ropivacaine-Neostigmine Injection for Perineal Analgesia at the End of Labor.

Perineal pain after childbirth occurs in the majority of women (with or without episiotomy). Perineal pain can become source of chronic pain in 9%-12% of the cases. Neostigmine a cholinesterase inhibitor at a dose of 500µg combined with Sufentanil or Ropivacaine (=local anaesthetic) is an analgesic. The goal of this …

  • 13 views
  • 07 Nov, 2020
  • 1 location
Wheelchair Maintenance Training Program

The objective of this research study is to assess the effectiveness of a remote wheelchair maintenance training program, and to determine methods which may increase overall success of an online training program.

  • 0 views
  • 24 Jan, 2021
  • 1 location
Evaluate Use of Caudal Nerve Blocks in Adult Penile Prosthesis

During penile prosthesis surgery, patients are given general anesthesia in combination with other pain drugs. A caudal nerve block (CNB) is a local anesthetic injected near the tailbone, in addition to general anesthesia, which can lower the need for pain drugs. The goal of this clinical research study is to …

  • 182 views
  • 22 Jan, 2021
  • 1 location
The Effect of Ultrasound Guided Superficial Deep Serratus Plane Blocks and Thoracic Epidural in Thoracotomy

Pain after thoracotomy is known to be sever acute pain that is resulted from retraction, resection or fracture of ribs .This pain increases post operative morbidity and if not properly managed peri-operatively, chronic post thoracotomy pain syndrome may develop. Different methods are described to manage post thoracotomy pain.Thoracic epidural analgesia …

  • 35 views
  • 23 Jan, 2021
  • 1 location
Pathophysiological Mechanism Behind Prolonged Whiplash Associated Disorders

The knowledge of pathophysiological mechanisms behind prolonged Whiplash Associated Disorders (WAD) is insufficient and whether changes can be restored by rehabilitation or not is unknown. The aim of these studies are to investigate different parameters to further learn about pathophysiological mechanisms (neck muscle fatty infiltration, cross-sectional area, volume, inflammation and …

  • 1 views
  • 26 Feb, 2021
  • 1 location
Study of the Safety and Effectiveness of NXN-188 for the Acute Treatment of Migraine Attacks With Aura

The following study is being conducted to explore the safety and effectiveness of a new chemical entity called NXN-188 in subjects with a history of migraine with aura. In this study subjects will treat two attacks of migraine with aura during the aura phase - once with placebo and once …

headache
dysphasia
implanon
hysterectomy
acute treatment
  • 8 views
  • 07 Nov, 2020
  • 1 location
Botulinum Toxin A for the Treatment of Chemotherapy Induced Peripheral Neuropathy

Chemotherapy induced peripheral neuropathy (CIPN) is a common side effect of taxanes and platinum derivative based chemotherapeutic agents, common in breast cancer treatment regimens. It can have a significant effect on both quality of life and treatment outcomes, often resulting in dose modifications and early treatment discontinuation. The use of …

cancer treatment
incobotulinumtoxina
neuralgia
cancer
nerve conduction studies
  • 0 views
  • 25 Jan, 2021
  • 1 location
A Phase II Study of Combine Modality Therapy in Locally Advanced Pancreatic Cancer

Induction chemotherapy will be administered every 2 weeks for 6 cycles (about 3 months). Patients who have radiological evidence of progressive disease will be shifted to salvage chemotherapy. Patients who have responsive or stable disease after induction chemotherapy will receive concurrent chemoradiotherapy 3-4 weeks after the last dose of induction …

measurable disease
leucovorin
oxaliplatin
immunostimulant
chemoradiotherapy
  • 11 views
  • 07 Nov, 2020
  • 2 locations
EuroPainClinics Study I (Prospective Trial)

In this prospective multi-centre double-blind trial the effect of the X-ray examinations controlled periradicular therapy should be examined in (approximately 300) adult patients with low back pain pain caused by foraminal stenosis radiculopathy or spinal stenosis. A periradicular therapy (PRT) is a special radiological, low-risk therapy for chronic back pain …

back pain
radiculopathy
x-rays
  • 0 views
  • 24 Jan, 2021
  • 2 locations