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Found 34 clinical trials
The Duration of External Neck Stabilisation (DENS) Trial (DENS)

The Duration of External Neck Stabilisation (DENS) study is a randomised controlled trial comparing early removal of a hard collar with treatment in a hard collar for 12 weeks in older or frail adults with odontoid (dens) fractures. The primary outcome measure is QoL assessed using the EQ-5D-5L at 12 …

  • 0 views
  • 27 Apr, 2022
  • 1 location
Microbiota and Bone Fragility:Study of the Relation Between Gut Microbiota and Bone Microarchitecture (MICROBONE)

fracture. the participants will have diagnostic exams: clinical tests, bone densitometry (body composition, vertebral fractures), high resolution peripheral QCT (bone strength estimated by microfinite

postmenopausal osteoporosis
quantitative computed tomography
spinal fracture
bone mineral density
bone densitometry
  • 227 views
  • 26 Feb, 2022
  • 1 location
Novel Combination Therapy for Osteoporosis in Men (Osteo-Men)

Osteoporotic fractures are a key health problem in older men. Although there are drugs approved to treat osteoporosis in men [bisphosphonates, denosumab, and teriparatide (TPTD) or PTH(1-34)], there is a lack of knowledge on how to use them effectively. TPTD is a potent bone anabolic drug, meaning that it builds …

  • 34 views
  • 26 Feb, 2022
  • 1 location
Percutaneous Kyphoplasty Using Rotary Cutter in Osteoporotic Vertebral Fractures

Kyphoplasty(PKP) is performed under general anaesthesia in patients with osteoporotic vertebral compression fracture. The balloon is first placed into the fractured vertebra and inflated with

  • 0 views
  • 22 Jan, 2021
  • 1 location
Surgical Treatment of the Thoracolumbar Spine Fractures.

The thoracolumbar segment fractures are the most frequent along the spine, and surgical treatment is indicated in unstable fractures. Surgical treatment has been performed through the posterior fixation pedicle fixation systems, and where necessary complemented by decompression of the spinal arthrodesis and previous channel. Surgical treatment has been performed by …

open surgery
ct scan
  • 2 views
  • 31 Jan, 2022
  • 1 location
ORthosis vs No Orthosis After Surgically Treated Traumatic Thoracolumbar Fractures (ORNOT)

the VU university medical centre, 18 - 65 years old with a traumatic thoracolumbar spine fracture from Th7 - L4 surgically treated by posterior fixation. Intervention: One group receives

kyphosis
stabilization of spine
pain relief
analgesics
conservative management
  • 2 views
  • 25 Feb, 2022
  • 1 location
Study of the AGN1 LOEP SV Kit in Patients With Vertebral Compression Fractures

This study is a prospective, single-arm, multi-center, European clinical study designed to evaluate the clinical performance and safety of the AGN1 LOEP SV Kit for the treatment of painful VCFs.

  • 0 views
  • 29 Jul, 2021
  • 1 location
Examination of Vertebroplasty in Addition to Regular Treatment of Patients With Multiple Myeloma.

Patients with newly diagnosed or known multiple myeloma with newly diagnosed vertebral lesion(s) will be invited to participate in a cross-sectoral randomized controlled trial. The trial will compare two groups of patients which either receive regular medical treatment of their vertebral lesion(s) or vertebroplasty in addition to regular medical treatment. …

  • 0 views
  • 29 Sep, 2021
  • 1 location
Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

This multicenter study will enroll 100 patients with acute traumatic cervical and thoracic SCI who have a lumbar intrathecal catheter inserted within 24 hours of their injury. The lumbar intrathecal catheter will be inserted pre-operatively for the measurement of ITP and the collection of cerebrospinal fluid (CSF) samples. SCPP will …

spinal cord disorder
spinal cord
  • 0 views
  • 11 Dec, 2021
  • 8 locations
A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)

mineral density returns to the pre-treatment value, and multiple vertebral fractures may occur. Recently, a guideline to administer bisphosphonates sequentially when Dmab is discontinued has been

  • 0 views
  • 11 May, 2022
  • 1 location