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Found 219 clinical trials
Featured trial
Multiple Sclerosis

perception of spasticity frequency and severity, walking impairment, sleep quality, muscle tone, pain levels, and psychiatric (mental) assessments, as well as the safety and tolerability. Insurance is not

spasticity
  • 0 views
  • 28 Oct, 2021
  • 1 location
Featured trial
An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis

An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing

  • 182 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Placebo-controlled Randomized Withdrawal Evaluation of the Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis

A Placebo-controlled Randomized Withdrawal Evaluation of the Efficacy and Safety of Baclofen ER Capsules (GRS) in Subjects With Spasticity Due to Multiple Sclerosis

  • 134 views
  • 08 Nov, 2020
  • 1 location
Featured trial
CHAMP Project (Child Hand Arm Movement Project)

CHAMP Project (Child Hand Arm Movement Project)

  • 668 views
  • 08 Nov, 2020
  • 1 location
None
A Study to Assess the Safety and Efficacy of IPN10200 of in Adult Participants With Upper Limb Spasticity.

IPN10200 doses(s) that offer the best efficacy/safety profile when used for the treatment of Adult upper limb (AUL) spasticity.

  • 0 views
  • 18 Nov, 2021
  • 37 locations
None
A Study to Compare the Safety and Efficacy of Dysport and Botox in Adults With Upper Limb Spasticity.

This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each …

  • 0 views
  • 01 Dec, 2021
  • 15 locations
None
Study to Compare the Efficacy and Safety of NT 201 (Botulinum Toxin) With Placebo for the Treatment of Lower Limb Spasticity Caused by Stroke or Traumatic Brain Injury

limb spasticity caused by stroke or traumatic brain injury (Main Period). Participants will be assigned to the treatment groups by chance and neither the participants nor the research staff who

  • 64 views
  • 08 Dec, 2021
  • 64 locations
None
Peripheral Modulation of Muscle Stiffness and Spasticity

This is a single-center, double-blind, randomized, placebo-controlled, cross-over Phase II trial of human recombinant hyaluronidase injections in individuals with post-stroke upper limb muscle stiffness. The investigators will recruit 50 subjects, 25 males and 25 females, who will be randomized to receive either hyaluronidase plus saline (treatment arm, n=25) or normal …

  • 0 views
  • 05 Nov, 2021
  • 1 location
None
Efficiency of the Super Inductive System in Spasticity Treatment

The aim of the study is to see whether a physical therapy program can relieve pain, decrease spasticity and increase muscle contraction force by using the super inductive system (high frequency

stroke
relieve pain
  • 0 views
  • 13 Apr, 2021
  • 1 location
None
Efficacy and Safety Study of MYOBLOC in the Treatment of Adult Lower Limb Spasticity

Multicenter, randomized, double-blind, placebo-controlled study of the safety and efficacy of single-dose MYOBLOC over a 1-year duration in adult subjects with lower limb spasticity, followed by

hemiplegia
myobloc
traumatic brain injury
stroke
  • 0 views
  • 25 Jul, 2021
  • 4 locations