Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 203 clinical trials
Featured trial
Multiple Sclerosis

perception of spasticity frequency and severity, walking impairment, sleep quality, muscle tone, pain levels, and psychiatric (mental) assessments, as well as the safety and tolerability. Insurance is not

spasticity
  • 0 views
  • 28 Oct, 2021
  • 1 location
Featured trial
An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing Arbaclofen Placarbil Safety in Subjects With Spasticity Associated With Multiple Sclerosis

An Open Label, 26-Week Study Assessing Arbaclofen Placarbil Safety and Efficacy in Subjects With Spasticity Associated With Multiple Sclerosis With an Addendum Open-Label, 36-Week Study Assessing

  • 207 views
  • 08 Nov, 2020
  • 1 location
Featured trial
CHAMP Project (Child Hand Arm Movement Project)

CHAMP Project (Child Hand Arm Movement Project)

  • 694 views
  • 08 Nov, 2020
  • 1 location
  • 4 views
  • 17 Sep, 2022
  • 27 locations
A Multicentre, Interventional, Post-marketing, Randomised, Double-blind, Crossover Study to Evaluate the Clinical Safety and Efficacy of AbobotulinumtoxinA (Dysport®) in Comparison With OnabotulinumtoxinA (Botox®) When Treating Adults With Upper Limb Spasticity (DIRECTION)

This study is aiming to demonstrate the non-inferiority of AbobotulinumtoxinA (aboBoNT-A) versus OnabotulinumtoxinA (onaBoNT-A) as the primary safety endpoint, and the superiority of aboBoNT-A over onaBoNT-A with respect to duration of response as the key secondary efficacy endpoint when used at optimal doses according to approved prescribing information of each …

  • 74 views
  • 15 Sep, 2022
  • 48 locations
Evaluation of the Effect of Nabiximols Oromucosal Spray on Clinical Measures of Spasticity in Participants With Multiple Sclerosis (RELEASE MSS5)

This study will be conducted to evaluate the effect of multiple doses of nabiximols compared with placebo on a clinical measure of velocity-dependent muscle tone in the lower limbs (Lower Limb Muscle Tone-6 [LLMT-6]) in participants with multiple sclerosis (MS). LLMT-6 is defined as the average of the 6 individual …

  • 0 views
  • 14 Jul, 2022
  • 18 locations
  • 144 views
  • 21 Sep, 2022
  • 47 locations
Peripheral Modulation of Muscle Stiffness and Spasticity

This is a single-center, double-blind, randomized, placebo-controlled, cross-over Phase II trial of human recombinant hyaluronidase injections in individuals with post-stroke upper limb muscle stiffness. The investigators will recruit 50 subjects, 25 males and 25 females, who will be randomized to receive either hyaluronidase plus saline (treatment arm, n=25) or normal …

  • 0 views
  • 24 Mar, 2022
  • 1 location
Efficiency of the Super Inductive System in Spasticity Treatment

The aim of the study is to see whether a physical therapy program can relieve pain, decrease spasticity and increase muscle contraction force by using the super inductive system (high frequency

stroke
relieve pain
  • 2 views
  • 04 Jun, 2022
  • 1 location
Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Lower Limb Spasticity

Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of lower limb spasticity, in adults

hemiplegia
traumatic brain injury
stroke
myobloc
  • 60 views
  • 13 Apr, 2022
  • 8 locations