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Found 7 clinical trials
Prospective Randomized Clinical Trial of Fetal Atrial Flutter & Supraventricular Tachycardia Therapy (FAST RCT)

with Digoxin or Sotalol (AF without hydrops); Digoxin or Flecainide (SVT without hydrops); and Digoxin plus Sotalol or Digoxin plus Flecainide (SVT with hydrops).

  • 373 views
  • 08 Feb, 2022
  • 19 locations
Pragmatic Randomized Clinical Trial of Early Dronedarone Versus Usual Care to Change and Improve Outcomes in Persons With First-Detected Atrial Fibrillation (CHANGE-AFIB)

While there are several completed clinical trials that address treatment strategy in patients with symptomatic and recurrent AF, there are no randomized clinical trials that address treatment for first-detected AF. In usual care, these patients are started on an atrioventricular nodal blocking agent (beta-blocker or non-dihydropyridine calcium channel blocker) along …

antiarrhythmic drug
beta blockers
stroke
fibrillation
dronedarone
  • 0 views
  • 19 Sep, 2022
  • 19 locations
Safety Assessment for Sotalol Protocol in Outpatient Unit (Sotalol)

Sotalol is an antiarrhythmic medication with proven effects for the suppression and prevention of supraventricular and ventricular arrhythmias. Due to its potential proarrhythmic effect, its

  • 0 views
  • 25 Jul, 2022
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

fibrillation
antiarrhythmic drug
flecainide
sotalol
  • 319 views
  • 08 Jul, 2022
  • 1 location
PRAGUE-25 Trial. Catheter Ablation vs. AADs and Risk Factor Modification.

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia with a prevalence of 2% in general population. Incidence and prevalence of AF has been slightly increasing due to increasing age, improved ability to treat cardiac diseases, and higher incidence of obesity and other risk factors associated with AF. AF …

antiarrhythmic drug
stroke
fibrillation
arrhythmia
heart failure
  • 0 views
  • 09 May, 2022
  • 1 location
Genetics of QT Prolongation With Antiarrhythmics (DOFEGEN)

To assess the ability of common genetic variants in aggregate to predict drug-induced QT prolongation in patients being loaded with dofetilide or sotalol.

antiarrhythmic drug
dofetilide
sotalol
  • 30 views
  • 26 Apr, 2022
  • 4 locations
Cardiac Arrhythmias In Patients With Coronavirus Disease (COVID-19)

The objective of the study is to estimate the frequency of cardiac arrhythmias and characterize the mode of death in patients with coronavirus disease (SARS-CoV-2; COVID-19). The study will also evaluate the long term cardiac outcomes in patients previously diagnosed with COVID-19. This is a single-center, retrospective/ prospective registry enrolling …

  • 50 views
  • 26 Apr, 2022
  • 1 location