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Found 69 clinical trials
OTL38 Injection (OTL38) for Intra-Operative Imaging of Folate Receptor Positive Ovarian Cancer

The primary objective of the study is to compare the performance of different camera imaging systems in assessing the positive predictive values and sensitivity of OTL38 to detect folate positive ovarian cancer cancers using the gold standard of pathologic review.

cancer of the ovary
tumor debulking
recurrent ovarian cancer
cytoreduction
  • 0 views
  • 22 Oct, 2021
  • 1 location
Reflux Band in Laryngopharyngeal Reflux

This 12 week biomarker targeted double blind randomized controlled trial (RCT) will enroll subjects with salivary pepsin positive laryngopharyngeal reflux (LPR) to assess efficacy of the external upper esophageal sphincter (UES) compression device, also known as the Reflux Band. Subjects will be randomized to one of two arms: control or …

  • 7 views
  • 04 Nov, 2021
  • 1 location
Clinical Trial of Immunogenicity Bridging of a Recombinant New Coronavirus COVID-19 Vaccine (CHO Cell)

Popular topic: A clinical trial comparing the immunogenicity of recombinant New Coronavirus vaccine (CHO cells) among people aged 3 to 17 and 18 to 59 years of age. Overall design:Non inferiority test design was used to evaluate the immunogenicity of the vaccine inoculated to the age group of 3~17 and …

Accepts healthy volunteers
  • 0 views
  • 28 Nov, 2021
  • 1 location
Comparing Photon Therapy To Proton Therapy To Treat Patients With Lung Cancer

This randomized phase III trial studies proton chemoradiotherapy to see how well it works compared to photon chemoradiotherapy in treating patients with stage II-IIIB non-small cell lung cancer that cannot be removed by surgery. Specialized radiation therapy that delivers a high dose of radiation directly to the tumor, such as …

carboplatin
x-rays
neutrophil count
scan with contrast
ct scan
  • 99 views
  • 27 Jan, 2021
  • 7 locations
Antiseptic Mouthwash / Pre-Procedural Rinse on SARS-CoV-2 Load (COVID-19) (AMPoL)

In this pilot trial, 150 confirmed COVID-19 individuals will be randomly assigned to 1 of 5 groups: distilled water, CloSYS Ultra Sensitive Rinse (Rowpar Pharmaceutical Inc., USA), Oral-B Mouth Sore (Oral-B, USA), Crest Pro-Health Multi-Protection (Crest, USA), or Listerine Zero (Johnson and Johnson, USA). Study participants will be asked to …

fatigue
covid-19
antiviral drugs
fever
SARS
  • 18 views
  • 06 Jun, 2022
  • 1 location
High vs. Standard Dose Influenza Vaccine in Adult SOT Recipients

The influenza virus is a significant cause of morbidity in adult solid organ transplant (SOT) recipients. However, these individuals show a suboptimal response to vaccines including the standard-dose (SD) inactivated influenza vaccine (IIV). Recent studies have investigated two strategies to overcome poor immune responses in SOT recipients: (1) administration of …

hemagglutination inhibition
vaccination
trivalent influenza vaccine
quadrivalent inactivated influenza vaccine
fluzone
  • 0 views
  • 17 Jun, 2022
  • 1 location
The MOTOR-CD Trial

Both single-balloon enteroscopy (SBE) and novel motorized spiral enteroscopy (NMSE) are effective techniques for small bowel endoscopy in suspected Crohn's disease (CD). Small bowel endoscopy is indicated for confirming diagnosis when CD is suspected based on clinical features along with cross-sectional small bowel imaging (computed tomography enterography/enteroclysis: CTE or magnetic …

crohn's disease
capsule endoscopy
endoscopy
  • 0 views
  • 28 May, 2022
  • 1 location
Fighting Immunosenescence and Promoting Immunity by a Fasting-mimicking Diet Elderly.

Background: Immunosenescence is an aging-dependent phenomenon underlying age dependent deterioration in the function of the immune system, characterized by a decline in B and T cells with a relative increase in natural killer (NK) cells. Aging also promotes chronic inflammation accompanied by increased levels of pro-inflammatory cytokines. Both immunosenescence and …

Accepts healthy volunteers
diabetes
cytokines
corticosteroids
fasting
  • 0 views
  • 31 Oct, 2021
  • 1 location
Pharmacogenetic Study of Antiarrhythmic Drugs for Atrial Fibrillation

In this pilot and feasibility study, the investigators will enroll patients with frequent symptomatic episodes of atrial fibrillation (AF) in a cross-over study testing two different classes of anti arrhythmic drugs (AADs). This pilot and feasibility study will provide preliminary data for a larger study in which the investigators will …

sotalol
antiarrhythmic drug
flecainide
fibrillation
  • 313 views
  • 24 May, 2022
  • 1 location
Gastroesophageal Function During Anesthesia

General anesthesia may predispose patients to aspiration of gastroesophageal contents because of depression of protective reflexes during loss of consciousness. The laparoscopy would increase the intra-abdominal pressure, which is regarded as a predisposing factor of gastroesophageal reflux during the anesthesia. The lower esophageal sphincter is the important physiological mechanisms that …

  • 24 views
  • 01 Mar, 2022
  • 1 location