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Found 29 clinical trials
Effect of Preoperative Oral Pregabalin Versus Intraoperative Fentanyl on Postoperative Analgesia

, respiratory depression, pruritus, and urinary retention.The concomitant use of opioids with pregabalin may result in excess sedation and somnolence, so, the use of opioids with pregabalin should be limited to

Accepts healthy volunteers
  • 0 views
  • 14 Apr, 2022
Mindfulness - Based Intervention in the Treatment of Fatigue in Patients With Primary Biliary Cholangitis

To assess the efficacy of mindfulness-based intervention (MBI) intervention in the treatment of moderate or severe fatigue in patients with primary biliary cholangitis (PBC).

cholangitis
cirrhosis
ursodiol
fatigue
  • 1 views
  • 01 Feb, 2022
  • 1 location
Ephedrine Versus Ondansetron During Cesarean Delivery

More than 30% of the patients receiving spinal anesthesia develop hypotension. Hypotension developed during cesarean section (C/S) under spinal anesthesia may jeopardize uteroplacental circulation leading to fetal compromise and even fetal death. The effect of prophylactic ondansetron on blood pressure after spinal anesthesia has not been compared in a clinical …

  • 0 views
  • 23 Mar, 2022
  • 1 location
Dissecting the Heterogeneity of Oral Cancer Pain

Oral squamous cell carcinoma (SCC) produces a higher prevalence and more severe pain than all other cancers. Orofacial pain is one of the most common initial symptoms of oral cancer and often leads to the diagnosis of oral cancer. However, the character, severity, and unique features of oral cancer widely …

  • 0 views
  • 04 Sep, 2021
  • 1 location
Constitution of a Clinical, Neurophysiological and Biological Cohort for Chronic Sleep Disorders Responsible of Hypersomnolence (Somnobank)

Chronic sleep disorders result from multiple pathophysiological mechanisms and are often associated with severe hypersomnolence, responsible for major disability. Hypersomnolence may be secondary to sleep disturbances at night by sleep fragmentation, both overall in restless leg syndrome (RLS) or specific to slow or paradoxical sleep in parasomnias (sleepwalking, sleep behavior …

  • 175 views
  • 11 Feb, 2022
  • 1 location
Tranexamic Acid to Prevent OpeRation in Chronic Subdural Hematoma (TORCH)

Rationale: Chronic subdural hematoma (cSDH) is a frequently occurring disease, occurring mainly in the elderly. Surgical evacuation is effective, but also associated with life-threatening risks. In these old, often frail, patients with multi-comorbidity, surgery also comes with significant risks for future cognitive functioning and therefore, loss of independency. In five …

  • 18 views
  • 25 Mar, 2022
  • 1 location
Integral Physiological Adaptations to Carbohydrate Periodization (IPACP)

The purpose of this study is to examine the effect of long-term carbohydrate periodization protocols on sleep architecture, sleep quality, daytime sleepiness, physical performance, body composition, gut microbiome, and miRNA in healthy trained individuals.

Accepts healthy volunteers
  • 0 views
  • 20 Jul, 2022
  • 1 location
Sleep Apnea in Head and Neck Cancer Patients at the University of Colorado (OSA-HN)

understood. OSA is identified as a contributing factor for daytime somnolence and quality of life (QOL), yet treatment of OSA in the SCCHN population has not been studied. The investigators hope to identify

carcinoma
cancer of the head
head and neck cancer
cancer
neck cancer
  • 0 views
  • 25 Mar, 2022
  • 1 location
Normotensive OSA Patients With Nondipper Circadian Blood Pressure Pattern (Nondipper-OSA)

, parallel, prospective, randomized and controlled trial including normotensive patients with nondipper circadian pattern diagnosed with severe SAHS without significant somnolence. 64 patients with nondipper

somnolence
continuous positive airway pressure
hypopnoea syndrome
polysomnography
  • 1 views
  • 23 Feb, 2022
Normotensive OSA Patients With Dipper Circadian Blood Pressure Pattern

, prospective, randomized and controlled trial including normotensive patients diagnosed with severe SAHS without significant somnolence. 64 patients with dipper circadian pattern will be included and will be

polysomnography
continuous positive airway pressure
hypopnoea syndrome
somnolence
  • 3 views
  • 13 May, 2022
  • 1 location