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Found 109 clinical trials
Fiber Intervention on Gut Microbiota in Children With Prader-Willi Syndrome

Prader-Willi syndrome (PWS) is the most common syndromic cause of obesity. Individuals with PWS characteristically experience excessive weight gain and severe hyperphagia with food compulsivity in early childhood, which often leads to the onset of obesity and metabolic complications. The pathogenesis of hyperphagia and progressive weight gain in PWS is …

chromosome analysis
body mass index
fasting
growth hormone
  • 0 views
  • 22 Apr, 2022
  • 1 location
Manipulating Ghrelin Signaling Via GOAT Inhibition in Alcohol Use Disorder

Background People with alcohol use disorder (AUD) have trouble controlling their drinking. Medications can help some people with AUD but are not effective for many others. Researchers want to test new drugs to better treat the disease. Objective To see if the investigational drug GLWL-01 is safe to use in …

  • 0 views
  • 24 May, 2022
  • 1 location
BFRT in Adolescents After ACL Reconstruction

This is an interventional study that will examine effects of blood flow restriction training (BFRT) in adolescents aged 12-18 after anterior cruciate ligament reconstruction surgery (ACLR). The study aims to identify the effect of BFRT on quadriceps muscle strength and the patient's quality of life, and the overall tolerability of …

  • 0 views
  • 13 Aug, 2021
  • 1 location
INTERVAL - Intense Exercise Trial for Men With Metastatic Castrate-Resistant Prostate Cancer

Exercise has been established to be safe and result in improved physical function and quality of life for most individuals with cancer. However, little information exists regarding whether exercise can increase overall survival and reduce disease progression, events related to cancer spreading to the bones (e.g. bone fracture, spinal cord …

adenocarcinoma of prostate
adenocarcinoma
gonadotropin
apalutamide
hormone therapy
  • 162 views
  • 25 Jan, 2021
  • 4 locations
A Study in Radiotherapy-related Nervous System Complications

Purpose: This observational study aims to evaluate the clinical manifestations, therapeutic effects, progress and prognosis in radiotherapy-related nervous system complications. OUTLINE: This is an observational clinical trial. Patients are enrolled and administrated with optimized clinical treatment. Blood, urine, stool, cerebrospinal fluid (CSF), imaging and other examinations, and scale assessments are …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Long-Term Follow-Up of Survivors of Pediatric Cushing Disease

Background The pituitary gland produces hormones. A tumor in this gland can cause it to produce too much of the hormone cortisol. Too much cortisol in the body causes Cushing disease. This disease causes many problems. Some of these problems might persist after the disease is cured. Objective To find …

dxa scan
stimulation test
cushing's syndrome
Accepts healthy volunteers
pituitary
  • 104 views
  • 15 May, 2022
  • 1 location
Peri-operative Dynamics of the Growth Hormone Axis in Subjects With Acromegaly

Acromegaly is a rare disorder characterized by excessive production of growth hormone most often by a pituitary adenoma. A pituitary adenoma is a tumor, almost always benign or non-cancerous

insulin-like growth factor
adenoma
oral glucose tolerance test
growth hormone
somatomedin c
  • 73 views
  • 24 Jan, 2022
  • 1 location
Micromegaly and Discrepancy Between Growth Hormone and IGF1 at the Diagnosis and Follow-up of Acromegalic Patients

The diagnosis and the follow-up of acromegalic patients are based on the mesurement of Growth hormone (GH) and IGF1 rates. However, the literature described some cases of patient for whom the

  • 0 views
  • 02 May, 2021
  • 1 location
A Prospective Study of Outcome After Therapy for Acromegaly

surgical or other treatment. This study is designed to determine blood levels of growth hormone and related hormones and cardiovascular risk markers as well as signs and symptoms of the disease at

oral glucose tolerance test
hepatic disease
growth factor
medical therapy
growth hormone
  • 131 views
  • 21 Jul, 2021
  • 1 location
Developing a Simple Recognition System of Acromegaly

We will compare the features of 3D stereophotography of acromegaly patients with that of healthy people. We hope to develop a computerized model to help screening acromegaly patients for early detection and treatment.

  • 46 views
  • 21 Jan, 2021