somatotropin Clinical Research Trials

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Advanced Filters

Found 137 clinical trials

None

For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Fetoscopic Endoluminal Tracheal Occlusion

The purpose of this research study is to see if the FETO surgery and FETO release (surgery to remove the device) works and is safe for babies with severe right or left Congenital Diaphragmatic Hernia (CDH). CDH is a condition in which a hole in the baby's diaphragm allows the …

pulmonary hypoplasia

diaphragmatic hernia

0 views
02 Jul, 2021
1 location

None

For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH

Congenital diaphragmatic hernia (CDH) occurs when the diaphragm fails to fully fuse and leaves a portal through which abdominal structures can migrate into the thorax. In the more severe cases, the abdominal structures remain in the thoracic cavity and compromise the development of the lungs. Infants born with this defect …

hypertension

diaphragmatic hernia

0 views
27 Apr, 2021
1 location

None

For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH)

This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100) at Michigan Medicine. The study will enroll pregnant women that meet study criteria. Participants will have …

pulmonary hypoplasia

diaphragmatic hernia

0 views
21 Apr, 2021
1 location

None

For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia

The goal is to assess the feasibility and safety of implementing Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in fetuses with severe left Congenital Diaphragmatic Hernia (CDH) at UTHealth. UTHealth's success in this study (with an initial 5 patients) will determine the feasibility of UTHealth's future participation in multi-center trials of …

pulmonary hypoplasia

diaphragmatic hernia

0 views
11 Mar, 2021
1 location

None

For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the …

prenatal

MRI

pulmonary hypoplasia

fetal therapy

nitric oxide

7 views
14 Oct, 2021
1 location

None

For pediatric ages
Recruiting in 10s
Interventional Study
For all genders
Endocrinology
Recruiting

CDH - Optimisation of Neonatal Ventilation

To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.

diaphragmatic hernia

2 views
22 Jan, 2021
1 location

None

Phase 1
For pediatric ages
Recruiting in 10s
Interventional Study
For all genders
Endocrinology
Recruiting

Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

The purpose of this study is to investigate the use of autologous umbilical cord blood (UCB) mononuclear cells to mitigate hypoxic neurologic injury among infants with high-risk congenital diaphragmatic hernia (CDH).

arterial blood gas

mononuclear cells

diaphragmatic hernia

21 views
17 Mar, 2021
1 location

None

For Seniors
For adults
Recruiting in 10s
Interventional Study
For Females
Endocrinology
Recruiting

Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH)

Despite advances in prenatal diagnosis and postnatal therapies, including ECMO (Extracorporeal Membrane Oxygenation), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with severe CDH remain high. The rationale for fetal therapy in severe CDH is to promote adequate lung growth …

0 views
26 Jan, 2021
1 location

None

For pediatric ages
Recruiting in 10s
Interventional Study
For all genders
Endocrinology
Recruiting

High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia

The purpose of this study is to conduct a prospective study of all congenital diaphragmatic hernia (CDH) neonates managed at the University of Utah newborn intensive care unit (NICU) and Primary Children's Hospital NICU that required mechanical ventilation at birth. As both high frequency jet ventilation (HFJV) and high frequency …

0 views
14 Mar, 2021
2 locations

None

For adults
Recruiting in 10s
Interventional Study
For all genders
Endocrinology
Recruiting

Bisphenol A and Muscle Insulin Sensitivity

This study examine oral bisphenol A consumption on muscle insulin sensitivity and hepatic glucose suppression. Half of the participants will receive a diet plus BPA and the other half will receive a diet plus no bisphenol A.

0 views
03 Feb, 2021
1 location