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Found 126 clinical trials
A Pilot Study of Empagliflozin in the Treatment of Acromegalic Cardiomyopathy

Acromegaly is a disease characterized by excess growth hormone(GH) and insulin like growth factor(IGF)-1. Pituitary GH secreting adenoma is the major cause of acromegaly. Acromegalic

somatostatin
cardiomyopathy
heart failure
growth hormone
growth factor
  • 692 views
  • 25 Jan, 2021
  • 1 location
Thymus Regeneration Immunorestoration and Insulin Mitigation Extension Trial

, cardiovascular disease, diabetes, dementia, and also infectious diseases, including flu and COVID-19. The study uses multiple agents in combination with personalized doses of recombinant human growth

  • 46 views
  • 02 Sep, 2021
  • 1 location
Evaluating the Impact of Focused Muscle Contraction Therapy in U.S. Veterans

This research study is being done to investigate if the GH Method exercise program positively affects body composition, improves physical abilities and can improve the overall sense of wellbeing

symptoms of stress
depressed mood
  • 0 views
  • 31 Oct, 2021
  • 1 location
Nutritional Stimulation of Growth in Children With Short Stature

the average weight of his/her peers). The growth hormone has limited efficacy for medical treatment of short stature when the cause of short stature is not growth hormone deficiency. This study will

  • 0 views
  • 29 Sep, 2021
  • 1 location
Fetoscopic Endoluminal Tracheal Occlusion

The purpose of this research study is to see if the FETO surgery and FETO release (surgery to remove the device) works and is safe for babies with severe right or left Congenital Diaphragmatic Hernia (CDH). CDH is a condition in which a hole in the baby's diaphragm allows the …

pulmonary hypoplasia
diaphragmatic hernia
  • 0 views
  • 02 Jul, 2021
  • 1 location
Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH

Congenital diaphragmatic hernia (CDH) occurs when the diaphragm fails to fully fuse and leaves a portal through which abdominal structures can migrate into the thorax. In the more severe cases, the abdominal structures remain in the thoracic cavity and compromise the development of the lungs. Infants born with this defect …

diaphragmatic hernia
hypertension
  • 0 views
  • 27 Apr, 2021
  • 1 location
Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH)

This is a single site pilot trial to assess the feasibility and safety of treating severe CDH with Fetal Endoscopic Tracheal Occlusion with the Goldballoon Detachable Balloon (GOLDBAL2) along with the Delivery Microcatheter (BALTACCI-BDPE100) at Michigan Medicine. The study will enroll pregnant women that meet study criteria. Participants will have …

pulmonary hypoplasia
diaphragmatic hernia
  • 0 views
  • 21 Apr, 2021
  • 1 location
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia

The goal is to assess the feasibility and safety of implementing Fetoscopic Endoluminal Tracheal Occlusion (FETO) therapy in fetuses with severe left Congenital Diaphragmatic Hernia (CDH) at UTHealth. UTHealth's success in this study (with an initial 5 patients) will determine the feasibility of UTHealth's future participation in multi-center trials of …

pulmonary hypoplasia
diaphragmatic hernia
  • 0 views
  • 11 Mar, 2021
  • 1 location
Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH)

Despite advances in prenatal diagnosis and postnatal therapies, including extracorporeal membrane oxygenation (ECMO), inhaled nitric oxide therapy, and ventilator strategies that minimize ventilator-induced lung injury, morbidity and mortality rates for babies with congenital diaphragmatic hernia (CDH) remain high. The survival relates to the degree of prenatal lung compression and the …

e 25
pulmonary hypoplasia
prenatal
MRI
nitric oxide
  • 7 views
  • 14 Oct, 2021
  • 1 location
Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH)

The purpose of this study is to investigate the use of autologous umbilical cord blood (UCB) mononuclear cells to mitigate hypoxic neurologic injury among infants with high-risk congenital diaphragmatic hernia (CDH).

mononuclear cells
diaphragmatic hernia
arterial blood gas
  • 21 views
  • 17 Mar, 2021
  • 1 location