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Found 109 clinical trials
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA

The research is aimed at identifying new predisposition genes for endocrine tumours. Our focus initially is on pituitary adenomas including growth hormone-secreting tumors (somatotrophinomas

adenoma
pituitary
growth hormone
prolactinomas
aip gene
  • 213 views
  • 23 Jan, 2022
  • 2 locations
Post-Market Clinical Follow-up Study of A-SPINE's Products

This is a post-market clinical follow-up study that use questionnaires such as Visual Analog Scale (VAS), the Neck Disability Index (NDI), or the Oswestry Disability Index (ODI) to compare the clinical improvement effects before and after surgery.

  • 0 views
  • 28 Apr, 2021
  • 1 location
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise

Each year world-wide, 2.5 million fetuses die unexpectedly in the last half of pregnancy, 25,000 in the United States, making fetal demise ten-times more common than Sudden Infant Death Syndrome. This study will apply a novel type of non-invasive monitoring, called fetal magnetocardiography (fMCG) used thus far to successfully evaluate …

holter monitor
prenatal
diagnostic procedure
electrocardiogram
  • 0 views
  • 15 Dec, 2021
  • 2 locations
Puberty, Diabetes, and the Kidneys, When Eustress Becomes Distress (PANTHER Study)

native kidney function, especially in youth with T2D. Puberty is a complex process of physiological changes, including neuroreproductive and growth hormone activation and rapid organ growth, that

glomerular filtration rate
dialysis
prediabetes
insulin resistance
diabetes
  • 0 views
  • 25 Mar, 2022
  • 1 location
Genetic Causes of Growth Disorders

Background Some growth disorders are caused by a change in genes. Genes are the instructions the body uses to function. Changes in genes often cause them not to work correctly. Researchers want to use a new technology called exome sequencing, to look at many genes at once. This is done …

growth hormone treatment
hormone deficiency
GH deficiency
hormone therapy
somatotropin
  • 72 views
  • 15 Jun, 2022
  • 2 locations
Hormonal and Inflammatory Changes During Pregnancy in Women With Glucose Metabolic Disorders.

The first aim of this study is to describe maternal hormonal and inflammatory changes during pregnancy in women that differ metabolically (limited to women with type 2 diabetes, gestational diabetes and/or overweight). The second aim of this study is to examine maternal hormonal, inflammatory and metabolic factors associated with insulin …

insulin
diabetes
  • 0 views
  • 03 Jul, 2021
  • 3 locations
LOng COvid COmorbidities: Endocrine,Metabolic,Neuropsychiatric,Muscle,Cardiovascular,Pulmonary,Dermatologic Dysfunctions (LO-COCO)

Considering the compelling amount of studies focused on patients in the active phase of COVID-19 disease and the scarcity of studies focused on patient cured from disease aimed at evaluating the sequelae of SARS-CoV-2 infection, the purpose of the study is to investigate whether in patients recovered from COVID-19 disease, …

  • 0 views
  • 24 Apr, 2022
  • 1 location
Mechanisms Behind Severe Insulin Resistance During Pregnancy in Women With Glucose Metabolic Disorders (SIR-MET)

The aim of this study is to describe the metabolic changes during pregnancy in women with type 2 diabetes or gestational diabetes in order to detect the pathophysiological mechanisms behind severe insulin resistance during pregnancy as well as the short- and long term consequences for mother and child. Included pathophysiological …

insulin
insulin resistance
prenatal
diabetes
  • 0 views
  • 26 Jun, 2021
  • 2 locations
Identification of miRNAs Associated With Gender Difference in Osteoarthritis Patients (MIRGOA)

The biological study involves the collection of samples from male and female patients (intraoperative waste tissue, blood and synovial fluid), suffering from mild and moderate-severe OA, who undergo endo or arthro-prosthesis surgery, or arthroplasty, for the identification and characterization of a panel of "gender-specific" miRNAs. MicroRNAs will be extracted from …

joint reconstruction
  • 0 views
  • 06 Apr, 2022