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Found 2042 clinical trials
Remote Telemonitoring of Patient-Generated Physiologic Health Data and Patient-Reported Outcomes

This study examines at-home monitoring of patient-generated phsyiologic health data and patient-reported outcomes. Patient-generated health data using at-home monitoring devices and smart device applications are used more and more to measure value and quality in cancer care. This trial may show whether at-home monitoring programs can improve the care of …

cancer
primary cancer
cancer treatment
cancer care
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Natural History Study of Children and Adults With Adrenocortical Cancer

Background Adrenocortical cancer (ACC) is a rare tumor. The prognosis is very poor for people with advanced stages of ACC. Some people may live with ACC for years; others live for just months. Treatment options for ACC often do not work well. Researchers want to study the clinical course of …

cancer
solid tumors
  • 65 views
  • 22 Oct, 2022
  • 1 location
Consistency Between Treatment Responses in PDO Models and Clinical Outcomes in Gastric Cancer

Gastric cancer is the fourth leading cause of cancer-related death worldwide. Accurate assessment of the clinical responses to current treatment regimens is key to improving the prognosis and prolonging the survival of patients. In this study, two hundred and fifty patients with gastric cancer who ought to receive neoadjuvant therapy, …

oxaliplatin
paclitaxel
fluorouracil
endoscopic biopsy
gastric adenocarcinoma
  • 0 views
  • 24 Mar, 2022
  • 1 location
The Culture of Advanced or Recurrent Ovarian Cancer Organoids and Drug Screening

Most ovarian cancer will relapse after standard therapy. Patients with recurrent ovarian cancer are resistant to platinum. Due to the high heterogeneity between ovarian cancer, individual precise therapy is of great importance. The study will establish ovarian cancer organoids, whose original tissues from the patients with advanced or recurrent ovarian …

cancer of the ovary
recurrent ovarian cancer
  • 0 views
  • 10 Apr, 2022
  • 1 location
Nutritional Status in Neuroblastoma in Sao Paolo, Brazil

This study proposes to investigate the effect of treatment of neuroblastoma on nutritional status, assessed by body mass index (BMI) z score, and body composition evaluated by mid-upper arm circumference (MUAC), from diagnosis through 1-year post end of treatment. The study also aims to investigate the nutritional status and its …

cancer
high-risk neuroblastoma
  • 7 views
  • 12 Feb, 2022
  • 1 location
Next-Generation Sequencing-based Germline and Somatic Genetic Testing in Triple-negative Breast Cancer (PERSONA)

For patients with triple negative breast cancer, implementation of genetic testing in decision making might impact both risk management for the patient and her family, but also, importantly, therapeutic management. Identifying genetically predisposed subjects dictates risk-reducing strategies that may imply bilateral salpingo-oophorectomy and mastectomy or long term medical approaches. In …

erbb2
triple-negative breast cancer
epidermal growth factor receptor
breast cancer
estrogen receptor
  • 0 views
  • 03 Feb, 2022
  • 1 location
Imaging Biomarkers for Immune Checkpoint Inhibitor Treatment in Patients With Non-small Cell Lung Cancer (IBFIC)

Hypothesis : imaging biomarkers of tumor measured by F-18 fluorodeoxyglucose (FDG) positron emission tomography(PET)/computed tomography(CT) is correlated with immune checkpoint inhibitor (ICI) treatment response and patient prognosis. Purpose: To evaluate the association between metabolic imaging parameters measured by F-18 FDG PET/CT and clinical outcomes in patients with non-small cell lung …

squamous cell carcinoma
pembrolizumab
lung carcinoma
atezolizumab
nivolumab
  • 0 views
  • 10 Jul, 2022
  • 1 location
Pathological Fracture in Potentially Unstable Spinal Metastases of Breast Cancer

The purpose of this study is to identify potential risk factors for and determine the rate of pathological fracture for patients which having spine metastases from breast cancer and be defined as potentially unstable (SINS 7-12) according to the Spinal Instability Neoplastic Score (SINS). The investigators' analysis will provide robust …

cancer
metastasis
breast cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
Clinical Value of MRD Monitoring for Adjuvant Therapy in Postoperative NSCLC

This clinical trial aims to explore the minimal residual disease (MRD) status of early NSCLC after curative surgery and the clinical outcomes of adjuvant chemotherapy. Next-generation sequencing technique will be used to examine the circulating tumor DNA (ctDNA) from MRD of 150 postoperative patients with stage IB-IIA NSCLC who received …

cancer chemotherapy
adjuvant chemotherapy
  • 0 views
  • 01 Jan, 2022
  • 1 location
Natural History Study of Children and Adults With Chordoma

Background Chordoma is a rare type of bone cancer. It occurs in the skull base or spine. Researchers want to study people with chordoma in different ways. They hope this will help them design better future treatments and supportive care studies for this disease. Objective To learn more about chordoma …

cancer
ct scan
  • 42 views
  • 27 Oct, 2022
  • 1 location