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Found 1709 clinical trials
featured
Advanced EGFR-positive Solid Tumor Malignancies

People with tumors are asked to participate in a research study being conducted by Montefiore Medical Center.

  • 201 views
  • 08 Jul, 2020
  • 1 location
featured
Pediatric Patients with Advanced Solid Tumors and Hematological Malignancies

Children with advanced solid tumors and hematological malignancies are asked to participate in a research study being conducted by Cohen Children's Medical Center of New York.  

  • 20 views
  • 20 Feb, 2019
  • 1 location
featured
First-in-human study of ATR inhibitor BAY1895344 in patients with advanced solid tumors and lymphomas

The purpose of the proposed trial is to evaluate the safety and tolerability of BAY1895344, and to identify the maximum tolerated dose of BAY1895344 that could be safely given to cancer patients.  Further, the response of the cancer to the treatment will be determined.  

lymphomas
non-hodgkin's lymphoma
lymphoma
solid tumors
  • 30 views
  • 29 Dec, 2020
  • 13 locations
featured
An Open-Label, Dose-Escalation, Safety Tolerability Study of INCAGN01876 in Subjects With Advanced or Metastatic Solid Tumors

An Open-Label, Dose-Escalation, Safety Tolerability Study of INCAGN01876 in Subjects With Advanced or Metastatic Solid Tumors

advanced solid tumor
solid tumor
solid tumors
  • 80 views
  • 08 Dec, 2020
  • 7 locations
featured
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

Evaluates the safety, tolerability, pharmacokinetics, metabolites, pharmacodynamics, and clinical activity of MRTX849 in patients with advanced solid tumors with a KRAS G12C mutation. MRTX849 is

solid tumor
advanced solid tumor
malignant solid tumor
  • 405 views
  • 02 Feb, 2021
  • 66 locations
featured
A Phase 1/2 Study of HDAC Inhibitor, Mocetinostat, in Combination With PD-L1 Inhibitor, Durvalumab, in Advanced or Metastatic Solid Tumors and Non Small Cell Lung Cancer

A Phase 1/2 Study of HDAC Inhibitor, Mocetinostat, in Combination With PD-L1 Inhibitor, Durvalumab, in Advanced or Metastatic Solid Tumors and Non Small Cell Lung Cancer

  • 314 views
  • 23 Nov, 2020
  • 4 locations
featured
Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib in Children with Refractory Solid Tumors or Refractory Leukemias

Phase I Study of the RAF Kinase and Receptor Tyrosine Kinase Inhibitor Sorafenib in Children with Refractory Solid Tumors or Refractory Leukemias

  • 6 views
  • 08 Nov, 2020
  • 1 location
featured
A Phase 1/2 Trial of MRTX849 in Combination with TNO155 in Patients with Advanced Solid Tumors with KRAS G12C Mutation

Characterize the safety and tolerability, and evaluate Pharmacokinetics of MRTX849 in combination with TNO155 in patients with advanced solid tumor malignancies with KRAS G12C mutation.

malignant solid tumor
advanced solid tumor
solid tumor
solid tumors
  • 114 views
  • 19 Feb, 2021
  • 10 locations
featured
A Phase I, dose-escalation study investigating the safety and tolerability of intratumoral injection of an Fc-engineered anti-CD40 monoclonal antibody (2141-V11) in patients with cancer

The purpose of this study is to test the safety and tolerability of a new drug called 2141-V11 in participants who have skin lesions associated with their cancer. It will also test how the body processes the drug and whether 2141-V11 has cancer fighting activity in humans.  The study drug …

  • 43 views
  • 23 Nov, 2020
  • 1 location
featured
EAY131: Molecular Analysis for Therapy Choice (MATCH)

EAY131: Molecular Analysis for Therapy Choice (MATCH)

multiple myeloma
lymphoma
solid tumors
  • 98 views
  • 24 Nov, 2020
  • 1 location