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Found 57 clinical trials
Fecal Microbiota Transplantation for C. Difficile Infection in Solid Organ Transplant Recipients

The objective is to examine the effect of Fecal Microbiota Transplantation (FMT) compared with vancomycin for cure of recurrent C. diff infection (CDI) in solid organ transplant (SOT) recipients

  • 3 views
  • 12 Sep, 2021
  • 1 location
Safety and Tolerance of Immunomodulating Therapy With Donor-specific MSC in Pediatric Living-Donor Liver Transplantation

(stromal) cells (MSC) have potent immunomodulatory properties potentially promoting allograft tolerance and ameliorating toxicity of exposure to high dose CNI. Previous trials for non-solid organ

  • 9 views
  • 22 Jan, 2021
  • 1 location
The Effects of Tranexamic Acid or Placebo on Perioperative Bleeding in Adults Undergoing Liver Transplantation.

Around 230 million major procedures are performed worldwide each year. Postoperative complications after major surgery, especially in solid organ transplants, are associated with a significant

tranexamic acid
venous thromboembolism
clot
stroke
surgical blood loss
  • 0 views
  • 02 Sep, 2021
  • 1 location
Tabelecleucel for Solid Organ or Allogeneic Hematopoietic Cell Transplant Participants With Epstein-Barr Virus-Associated Post-Transplant Lymphoproliferative Disease (EBV+ PTLD) After Failure of Rituximab or Rituximab and Chemotherapy

lymphoproliferative disease (EBV+ PTLD) in the setting of (1) solid organ transplant (SOT) after failure of rituximab and rituximab plus chemotherapy or (2) allogeneic hematopoietic cell transplant (HCT) after

blood transfusion
chemotherapy regimen
deoxyglucose
platelet count
ct scan
  • 70 views
  • 08 Sep, 2021
  • 79 locations
Switch to Oral Antibiotics in Gram-negative Bacteremia

, central nervous system infection, terminal illness with expected survival less than 14 days, absolute neutrophil count less than 1,000/ml and hematopoietic or solid organ transplantation within the

  • 73 views
  • 10 Feb, 2021
  • 9 locations
A Study to Evaluate Tabelecleucel in Participants With Epstein-barr Virus-associated Diseases

The purpose of this study is to assess the efficacy and safety of tabelecleucel in participants with Epstein-Barr virus (EBV) associated diseases.

cancer
chemotherapy regimen
measurable disease
cancer chemotherapy
systemic disease
  • 0 views
  • 01 Sep, 2021
  • 23 locations
Solid Organ Transplant SHINGRIX

This study will assess the immune responses to the recombinant, AS01-adjuvanted varicella zoster virus subunit (HZ/su) vaccine or SHINGRIX in immunosuppressed patients, particularly those who have received a renal transplant, and to better understand if the vaccine and perhaps other adjuvanted vaccines are safe in these patients. 30 participants will …

vaccination
solid organ transplant
organ transplantation
immunosuppression
varicella
  • 10 views
  • 16 Feb, 2021
  • 4 locations
Spleen Transplant in Solid Organ Transplantation

Although the notions that kidney transplantation is the treatment of choice for patients with end-stage renal disease and that simultaneous kidney and pancreas transplant is the only treatment able to restore euglycemia in patients with type 1 diabetes and selected patients with type 2 diabetes, are now consolidated, rates of …

  • 0 views
  • 10 Apr, 2021
  • 1 location
Viral Specific T-cells for Treatment of Viral Infections After Solid Organ Transplant

The purpose of this research study is to learn more about the use of viral specific T-lymphocytes (VSTs) to treat viral infections that may happen after solid organ transplant (SOT). VSTs are

prednisone
cmv infection
fever
cns infection
nephropathy
  • 0 views
  • 13 May, 2021
  • 1 location
A Study of mDOT for Immunosuppressant Adherence in Solid Organ Transplant Recipients

In solid organ transplant recipients, poor adherence to immunosuppressant medications carries the risk of graft rejection (needing a new transplant), post-transplant complications, and increased

  • 0 views
  • 26 Jan, 2021
  • 3 locations