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Found 633 clinical trials
Featured trial
Seclidemstat in the treatment of Ewing sarcoma and other select sarcomas

'standard of care' treatment will depend on your type of sarcoma. The study doctor/staff will talk with you more about this.You will take the study medication twice a day throughout

  • 17 views
  • 04 Feb, 2022
  • 16 locations
Featured trial
COG D9902: Collecting and Storing Tissue, Blood, and Bone Marrow Samples from Patients with Rhabdomyosarcoma or Other Soft Tissue Sarcoma

COG D9902: Collecting and Storing Tissue, Blood, and Bone Marrow Samples from Patients with Rhabdomyosarcoma or Other Soft Tissue Sarcoma

  • 224 views
  • 08 Nov, 2020
  • 1 location
Featured trial
AEWS07B1: Collecting and Storing Biological Samples From Patients with Ewing Sarcoma

AEWS07B1: Collecting and Storing Biological Samples From Patients with Ewing Sarcoma

  • 60 views
  • 08 Nov, 2020
  • 1 location
Featured trial
AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

AEWS1031: A Phase III Randomized Trial of Adding Vincristine-Topotecan-Cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-Metastatic Ewing Sarcoma

  • 380 views
  • 08 Nov, 2020
  • 1 location
Trabectedin for Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma

The objective of this study is to facilitate access to trabectedin for eligible previously treated subjects with soft tissue sarcoma (STS), who cannot be expected to benefit from

soft tissue sarcoma
trabectedin
metastatic soft tissue sarcoma
  • 60 views
  • 07 Nov, 2020
  • 1 location
A Randomized Trial of Pembrolizumab & Radiotherapy Versus Radiotherapy in High-Risk Soft Tissue Sarcoma of the Extremity (SU2C-SARC032)

This is an open-label, multi-institutional phase II randomized study comparing neoadjuvant radiotherapy followed by surgical resection to neoadjuvant pembrolizumab with concurrent radiotherapy, followed by surgical resection and adjuvant pembrolizumab. The total duration of pembrolizumab will be one year in the experimental arm.

  • 56 views
  • 06 Apr, 2022
  • 16 locations
Long Term Brain Toxicity of Chemotherapy in Patients Treated for a Bone TumorDuring Childhood or Adolescence

To assess the neurocognitive outcomes in patients treated with chemotherapy for a malignant bone tumor during childhood and adolescence and the factors associated with neurocognitive impairment and/or complaints

  • 0 views
  • 15 Oct, 2021
  • 1 location
A Study of MK-1084 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With KRASG12C Mutant Advanced Solid Tumors (MK-1084-001)

This is a study evaluating the efficacy, safety, and pharmacokinetics of MK-1084 in participants with advanced solid tumors with identified kirsten rat sarcoma viral oncogene homolog G12C

  • 2 views
  • 09 Aug, 2022
  • 24 locations
EFFECTIVENESS SAFETY AND IMMUNOGENICITY OF THE HALF DOSE OF THE VACCINE ChadOx1 nCoV-19 (AZD1222) for COVID-19

interval of 8 weeks, including all adults aged 18 to 49 years from Viana city - Esprito Santo (ES)/Brazil, on the incidence of new cases over 12 months following treatment, compared to an external group

Accepts healthy volunteers
  • 6 views
  • 06 Oct, 2021
  • 1 location
Investigating Safety, Tolerability, Efficacy and PK of Olaparib in Paediatric Patients With Solid Tumours

A study to find out whether olaparib is safe and well tolerated when administered to children and adolescents with solid tumours.

  • 33 views
  • 06 Jun, 2022
  • 20 locations