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Found 19 clinical trials
Oral Moxifloxacin Versus Cefazolin and Oral Probenecid in the Management of Skin and Soft Tissue Infections in the Emergency Department

Patients often come to the emergency department with bacterial skin infections (known as "cellulitis"). Some patients with very severe infections are admitted to hospital for antibiotic treatment and some are sent home on oral antibiotics. Many patients have moderate infections and are treated as outpatients with daily intravenous antibiotics for …

cefazolin
antibiotics
skin infections
soft tissue infection
antibiotic therapy
  • 9 views
  • 07 Nov, 2020
  • 1 location
Initiating Substance Use Disorder Treatment for Hospitalized Opioid Use Disorder Patients.

The purpose of this 24-week study is to evaluate the impact of recovery coach intervention on rates of treatment retention, illicit opioid use, and readmission among hospitalized patients newly initiated on buprenorphine or methadone compared to the control intervention.

  • 2 views
  • 05 Feb, 2021
Safety Immunogenicity and Efficacy of GSK S. Aureus Candidate Vaccine (GSK3878858A) When Administered to Healthy Adults (Dose-escalation) and to Adults 18 to 50 Years of Age With a Recent S. Aureus Skin and Soft Tissue Infection (SSTI)

. aureus skin and soft tissue infection (SSTI). In the dose-escalation safety lead-in phase in healthy adults safety and immunogenicity of 4 different compositions is assessed. After safety has been shown

hysterectomy
cellulitis
abscess
drainage
bilateral ovariectomy
  • 7 views
  • 25 Jan, 2021
  • 1 location
Preventing Young Infant Infections Using Azithromycin in Labour (PreYIAL) Trial

A trial to assess cumulative incidence of skin and soft tissue infections (SSTI) in infants (by three months of age) born to mothers receiving a single-dose of 2 grams of oral azithromycin

antibiotics
  • 2 views
  • 24 Jan, 2021
  • 1 location
Vitamin D Supplementation in the Armed Forces

reduce stress fracture risk and susceptibility to skin, soft tissue infection (SSTI) and respiratory infection in Royal Marine recruits undertaking arduous physical training in a randomised control trial

serum pth
soft tissue infection
stress fracture
vitamin d supplementation
  • 55 views
  • 23 Jan, 2021
  • 1 location
Improving Safety of Diagnosis and Therapy in the Inpatient Setting

To improve the safety of diagnosis and therapy for a set of conditions and undifferentiated symptoms for hospitalized patients, the investigators will employ a set of methods and tools from the disciplines of systems engineering, human factors, quality improvement,and data analytics to thoroughly analyze the problem, design and develop potential …

chronic obstructive pulmonary disease (copd)
cough
deep vein thrombosis
delirium
obstructive lung disease
  • 87 views
  • 25 Jan, 2021
  • 1 location
Bacillus Calmette-gu rin Vaccination to Prevent COVID-19

Based on findings of the interim analysis of the ACTIVATE study showing 53% decrease of the incidence of all new infections with BCG vaccination, a new trial is designed aiming to validate if BCG can protect against COVID-19 (Corona Virus Disease-19).The aim of the study is to demonstrate in a …

heart disease
coronary artery disease
COPD
covid-19
bcg vaccine
  • 258 views
  • 25 Jan, 2021
  • 15 locations
Reinforced PTFE Meshes Versus Customized Titanium Meshes

The objective of this study is to compare two surgical techniques for the treatment of the maxillary and mandibular bone atrophies.. Therefore, the main purpose is to compare the (i) the percentage of post-operative complications (ii) the three-dimensional bone gain with customized titanium meshes (test group - the medical device …

partial edentulism
  • 1 views
  • 25 Jan, 2021
  • 1 location
Staph Household Intervention for Eradication (SHINE)

households and subsequently decrease the incidence of skin and soft tissue infections (SSTI).

soft tissue infection
mupirocin
cutaneous infections
chlorhexidine
decolonization
  • 18 views
  • 28 Jan, 2021
  • 2 locations
Delayed Primary Closure Using Negative Pressure Wound Therapy

between surgeons. Primary closure (PC) of these wounds can lead to multiple complications including surgical site infection (SSI), necrotizing soft tissue infection, wound and fascial dehiscence

  • 0 views
  • 26 Jan, 2021
  • 1 location