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Found 197 clinical trials
Biomarkers of Response to Systemic Treatments in FH-deficient RCC

Fumarate hydratase-deficient renal cell carcinoma (FH-deficient RCC) is a rare subtype of RCC characterized by germline/somatic mutation of the fumarate hydratase (FH) gene, and is an extremely aggressive tumor, with a propensity to disseminate early even in the setting of a small primary tumor. Affected individuals or individuals suspected of …

metastatic renal cell carcinoma
carcinoma
primary tumor
cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
Fecal Metabolome and the Intestinal Microbiota in Irritable Bowel Syndrome (IBS)

The purpose of this study is to find out the relationship between the bile acids, fatty acids (fatty acids are part of the diet) and bacteria that are present in the intestines.

Accepts healthy volunteers
fatty acids
microbiota
fodmap diet
bile acid
  • 219 views
  • 23 Feb, 2022
  • 1 location
Analysis of Human ALS Tissues and Registry of ALS Patients

Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig's Disease, is a progressive, terminal condition of muscle weakness that is associated with degeneration of neurons in the spinal cord and brain. This devastating disorder afflicts people in the prime of their lives. At the present time, there are no …

primary lateral sclerosis
weakness
spinal cord
  • 0 views
  • 10 Oct, 2021
  • 1 location
Observational Study of the Efficacy and Safety of Anlotinib Combined With Penpulimab in Elderly Lung Cancer Patients (AP)

This prospective observational study will evaluate the efficacy and safety of anlotinib in combination with Penpulimab in elderly patients with lung cancer. Data will be collected from each patient at baseline and after 4-6 cycles of therapy.

metastasis
lung carcinoma
cancer
neutrophil count
systemic therapy
  • 0 views
  • 09 Jun, 2022
  • 1 location
Fibroblast Activation Protein Inhibitor PET/CT Imaging in Malignant Tumor of Digestive System

The purpose of this single center prospective study is to assess the value of FAPI PET imaging in predicting early postoperative recurrence of malignant tumor of digestive system and to evaluate the diagnostic performance of FAPI PET/CT in the detection of primary tumor and metastatic lesions.

cancer
  • 0 views
  • 04 Oct, 2022
  • 1 location
Complement C5a Receptors in Hidradenitis Suppurativa

To study the role of C5a in Hidradenitis Suppurativa (HS). Complement C5a is a major chemotactic factor that stimulates neutrophil infiltration.

Accepts healthy volunteers
hidradenitis
  • 217 views
  • 11 Jul, 2022
  • 1 location
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN)

Despite advancements in medical care, ischemic heart disease (IHD) remains the leading global cause of death. IHD develops through lipid accumulation into the coronary arteries with subsequent formation of larger atherogenic plaques. During myocardial infarction (MI), a plaque ruptures and subsequent occlusion leads to a death of the heart muscle. …

  • 0 views
  • 26 Jan, 2021
  • 1 location