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Found 82 clinical trials
Coeliac Disease in the Nord-Trøndelag Health Study (HUNT)

participants and assessed for celiac disease by a serological assay. Celiac disease is a chronic inflammatory disease of the small intestine due to dietary gluten in wheat, barley and rye. The diagnosis will

serologic test
Accepts healthy volunteers
small intestine
duodenal biopsy
  • 17 Oct, 2022
  • 1 location
DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors

>Undifferentiated carcinoma of gastrointestinal (GI) tract Adenocarcinoma with variants of small intestine (closed to accrual 05/10/2018) Squamous cell carcinoma with variants of GI tract (stomach

gallbladder cancer
solid tumors
mucinous adenocarcinoma
  • 22 Oct, 2022
  • 752 locations
A Trial Comparing Observation With Radiation on Pelvic Lymphocysts After Radical Hysterectomy of Cervical Cancer

Cervical cancer of early stage is treated mainly by radical resection and (or) radiotherapy. And pelvic lymphocyst is one of the most common adverse events of radical resection. The aim of this study is to compare observation with radiation on pelvic lymphocyst of cervical cancer patients after radical resection, for …

treatment regimen
  • 21 Jan, 2021
  • 7 locations
An Open-Label Phase 2 Study of Surufatinib in Patients With Neuroendocrine Tumours in Europe

This is a Phase 2, open-label, multi-centre study of surufatinib in patients with low to intermediate grade (Grade 1 or Grade 2), well-differentiated neuroendocrine tumours (NETs).

  • 24 Oct, 2022
  • 17 locations
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE) (OligoRARE)

This is a randomized open-label multicentre Phase III superiority study of the effect of adding SBRT to the standard of care treatment on overall survival in patients with rare oligometastatic cancers. Patients will be randomized in a 1:1 ratio between current standard of care treatment vs. standard of care treatment …

brain metastases
systemic therapy
  • 26 May, 2022
  • 7 locations
Networks of Bacterium-Metabolite Interactions in the Small Intestine

Probands with an Ileo- or Colostomy are assigned to consume a test meal which is either high in fat or high in carbohydrates. After the test meal samples from the stoma, urine, blood and skin are retrieved. These will be subjected to large scale analyses of microbiota and metabolite content. …

Accepts healthy volunteers
  • 04 Jun, 2022
  • 1 location
A Phase Ib/II Trial of JAB-21822 in Combination With Cetuximab in Patients With Advanced Colorectal Cancer, Small Intestine Cancer and Appendiceal Cancer With KRAS G12C Mutation

This study is to evaluate the safety, tolerability, pharmacokinetics and antitumor activity of JAB-21822 in combination with cetuximab in patients with advanced colorectal cancer,advanced small

  • 16 Oct, 2022
  • 4 locations
Rifaximin and Misoprostol Combination Therapy for Healing of Small Bowel Ulcers in Aspirin Users

Background: Investigators have previously shown that misoprostol can heal small bowel ulcers in aspirin users with small bowel bleeding. However, the rate of small-bowel mucosal healing was low with use of misoprostol alone. There is evidence to suggest that bacteria contribute to the development aspirin-induced ulcers and antibiotics may be …

  • 25 Jan, 2021
  • 2 locations
Open Abdomen and Delayed Anastomosis After Anastomotic Dehiscences to Avoid Stomas (STOP-STOMA)

Phase III clinical trial to evaluate the efficacy of the open abdomen as bridging therapy to perform transit reconstruction in patients with anastomotic dehiscence. It is a randomized controlled single-center study that will be carried out at the Virgen del Rocío University Hospital in Seville.

  • 05 Jul, 2022
  • 1 location
Effects of Ondansetron on Gastrointestinal Sensorimotor Dysfunctions in Diabetes Mellitus and Dyspepsia

sensitivity to nutrients in the small intestine. As part of this investigation, a medication called ondansetron will also be studied to determine its effects on gastrointestinal function and associated

diabetes mellitus
ondansetron 8 mg
  • 02 Jun, 2022
  • 1 location