Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 187 clinical trials
Featured trial
A Phase 1/2 Multiple Expansion Cohort Trial of MRTX849 in Patients With Advanced Solid Tumors With KRAS G12C Mutation

an orally-available small molecule inhibitor of KRAS G12C.

solid tumor
advanced solid tumor
malignant solid tumor
  • 536 views
  • 22 Nov, 2021
  • 62 locations
Featured trial
Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer

Phase 2 Study of Glesatinib, Sitravatinib or Mocetinostat in Combination With Nivolumab in Non-Small Cell Lung Cancer

  • 356 views
  • 08 Nov, 2020
  • 2 locations
Featured trial
Eltrombopag Added to Standard Immunosuppression in Treatment-Naive Severe Aplastic Anemia

Background: Severe aplastic anemia is a rare and serious blood disorder. It happens when the immune system starts to attack the bone marrow cells. This causes the bone marrow to stop making red blood cells, platelets, and white blood cells. Standard treatment for this disease is horse-ATG and cyclosporine, which …

anemia
aplastic anemia
myelodysplastic syndrome (mds)
anemia studies
myelodysplastic syndromes
  • 172 views
  • 22 Dec, 2020
  • 1 location
A First-in-Humans Dose Finding Study for an Aryl Hydrocarbon Receptor Inhibitor (AhRi) in Patients With Advanced Cancer

, distributes and gets rid of the study dug. BAY2416964 is a small molecule which blocks the Aryl Hydrocarbon Receptor (a protein involved in immune cell reaction to tumor cells) allowing the body to use its

  • 43 views
  • 18 Apr, 2022
  • 16 locations
DFF332 as a Single Agent and in Combination With Everolimus & Immuno-Oncology Agents in Advanced/Relapsed Renal Cancer & Other Malignancies

This is first in human study of DFF332, a small molecule that targets a protein called HIF2α. By acting on HIF2α, DFF332 may be able to stop the growth of certain types of cancer. DFF332 will be

cancer
carcinoma
rad001
vegf
clear cell renal cell carcinoma
  • 16 views
  • 02 May, 2022
  • 8 locations
Adalimumab vs. Conventional Immunosuppression for Uveitis Trial (ADVISE)

immunosuppressive drugs. The ADVISE Trial is multicenter randomized, parallel-treatment, comparative effectiveness trial comparing adalimumab to conventional (small molecule) immunosuppression for corticosteroid

monoclonal antibodies
small molecule
azathioprine
tumor necrosis factor
methotrexate
  • 124 views
  • 18 Feb, 2022
  • 18 locations
Safety and Tolerability Study for T-1101 (Tosylate) Capsules to Treat Advanced Refractory Solid Tumors

T-1101 (Tosylate) is a new small molecule chemical entity being developed as a potential anti-cancer therapeutic by Taivex Therapeutics Corp. T-1101 (Tosylate) is a potent anti-cancer agent in

  • 0 views
  • 09 Nov, 2021
  • 2 locations
Niraparib in Combination With Cabozantinib (XL184) in Patients With Advanced Urothelial Cancer (NICARAGUA) (NICARAGUA)

Cabozantinib is an oral, small-molecule tyrosine kinase inhibitor. Its primary targets are Hepatocyte growth factor receptor protein (MET), vascular endothelial growth factor receptor 1-3

serum pregnancy test
hysterectomy
platinum-based chemotherapy
neutrophil count
gilbert's disease
  • 46 views
  • 26 Mar, 2022
  • 9 locations
Anesthesia on Gut Microbiota and Metabolomics

small-molecule metabolites has been an integral part of clinical practice including the familiar clinical standards like glucose and creatinine. Metabolomics, however, is able to measure all the

  • 0 views
  • 13 Apr, 2022
Radium-223 in Biochemically Recurrent Prostate Cancer

biochemically recurrent prostate cancer. Radium-223 is a small molecule. It uses radiation to kill cancer cells and improves survival in advanced prostate cancer. Researchers want to see if it can treat

  • 0 views
  • 09 May, 2022
  • 1 location