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Found 805 clinical trials
A Personalized Behavioral Intervention to Improve Physical Activity, Sleep and Cognition in Sedentary Older Adults

Americans, is an important risk factor for both cognitive decline and sleep disturbances. Although promoting physical activity has benefits to older adults' health, including sleep and cognition

Accepts healthy volunteers
  • 12 Feb, 2022
  • 1 location
Project Movement/Daily Move

meditation app, Calm, on various mental health outcomes in a diverse range of adults (cancer patients, adults with sleep disturbances, etc.). The investigators have found the Calm meditation app to be both

Accepts healthy volunteers
  • 12 Mar, 2022
  • 1 location
Effect of Aquatic Physiotherapy for People With Stress

validated questionnaire Cohen's Perceived Stress Scale (PSS). 2. Secondary effect measures: Change of sleep disorders from baseline using validated questionnaire Pittsburgh Sleep Quality

  • 11 Mar, 2022
Testing Scalable, IVR-supported Cancer Prevention Interventions in the Rural Alabama Black Belt

and 12 months than the wait list control arm. Exploratory Aims. Examine 1) Intervention effects on physical performance and psychosocial variables (anxiety, depression, fatigue, sleep

Accepts healthy volunteers
  • 11 May, 2022
  • 1 location
SIESTA: Sleep Intervention to Enhance Cognitive Status and Reduce Beta Amyloid

The objective of this study is to compare the efficacy of a sleep intervention on improving cognitive function in older adults with symptoms of insomnia, determine the association between change in sleep measures and change in cognitive function, and examine the efficacy of the sleep intervention on reducing the rate …

initial insomnia
Accepts healthy volunteers
cognitive therapy
behavior therapy
cognitive behavioral therapy for insomnia
  • 14 Feb, 2022
  • 1 location
Predictors of Response to Insomnia Treatments for Gulf War Veterans

The purpose of this study is to evaluate the efficacy and effectiveness of Sleep Restriction (SR) and Cognitive Therapy (CT) in Gulf War Veterans with insomnia. The primary hypothesis is that the efficacy of these treatments will depend upon an individual subject's baseline characteristics. For SR we expect that baseline …

cognitive therapy
behavior therapy
  • 25 Mar, 2022
  • 3 locations
Transcranial Magnetic Stimulation of the Default Mode Network to Improve Sleep

Insomnia is generally believed to be caused by excessive arousal of the brain and body. Rather than transitioning normally and quickly from wakefulness to sleep, individuals with insomnia tend to enter into a self-perpetuating cycle of self-referential thought and arousal. Brain imaging research has shown that these same internally focused …

primary insomnia
  • 22 Aug, 2021
  • 1 location
Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD (PRECEPT-D)

Obstructive sleep apnea (OSA) is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares. Continuous positive airway pressure (CPAP) is the most effective therapy but adherence to treatment is suboptimal. Insomnia is considered a barrier to long-term adherence. …

  • 20 Feb, 2022
  • 1 location
Prevention of Airway Obstruction Events

The standard for treatment for people suffering from obstructive sleep apnea (OSA) syndrome involves the use of Continuous, or Automatic Positive Airway Pressure (CPAP, APAP) machines, which work by delivering air via tubing and mask to a patient at pressures of up to 20cmH2O. This increased pressure is meant to …

  • 26 Apr, 2022
Sleep and Healthy Aging Research for Depression (SHARE-D) Study (SHARE-D)

Late-life depression is a significant public health concern, and effective interventions for prevention and treatment are needed. Insomnia and inflammation are modifiable targets for depression prevention, and this study is significant in using an experimental approach (i.e., inflammatory challenge) to probe acute inflammatory- and depression responses as a function of …

Accepts healthy volunteers
  • 03 Mar, 2022
  • 1 location