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Found 266 clinical trials
Sleep Quality Upper Airway and Dental Occlusion in Children With Large Overjet

This project examines sleep quality (e.g. prevalence of obstructive sleep apnea(OSA)), dimension of upper airway, jaw function, well-being and quality of life in children with large overjet

  • 23 Jul, 2021
  • 1 location
Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD (PRECEPT-D)

Obstructive sleep apnea (OSA) is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen

  • 20 Feb, 2022
  • 1 location
Rebreathing-induced Hypoxia and Glucose Levels

The aim of this research project is to determine the effect of repeated maximal voluntary apneas on glucose uptake during an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2 diabetes.

Accepts healthy volunteers
  • 30 Jun, 2022
  • 1 location
Steroid Eye Drops in Chronic Central Serous Chorioretinopathy (PICS)

In this pilot study the effect and safety of the use of steroid eye drops in chronic central serous chorioretinopathy (cCSC) will be evaluated. The study is conducted as a randomized single-blind placebo-controlled trial. Forty patients will be randomized to either steroid eye drops or placebo eye drops. Patients will …

  • 10 Apr, 2023
  • 1 location
SOLIDARITY Finland Long-COVID (Remdesivir Long-term Follow-up Study of COVID Patients)

SOLIDARITY Finland Long-COVID trial assesses the effects of remdesivir + standard of care (SoC) vs. only SoC on long-COVID symptoms and quality of life (QoL) using questionnaires at one and two years post-discharge. Objectives i) Long-COVID symptoms To investigate the effect of remdesivir (vs. SoC) on the occurrence of symptoms …

  • 04 Oct, 2022
  • 1 location
Technology-Supported Treatment of Sleep Apnea in Prediabetes (TECH)

to reduce its cardiovascular complications in this high-risk population. Sleep apnea is a highly common condition in prediabetes, but it has been mostly ignored and undertreated in current practice

  • 11 Oct, 2022
  • 1 location
Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy (SLEEP)

A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the

  • 06 Apr, 2023
  • 11 locations
A Post-market Clinical Follow up of the Genio™ System for the Treatment of Obstructive Sleep Apnea in Adults (EliSA)

The primary objective of this study is to confirm the safety and clinical effectiveness of the Genio™ system, used according to its instructions for use, in moderate to severe Obstructive Sleep

body mass index
  • 21 Mar, 2022
  • 6 locations
DISE: Phenotyping Obstruction Patterns (DISE-PhOP)

Drug-induced sleep endoscopy (DISE) represents an opportunity to evaluate the upper airway in sleep-like conditions. In its current clinical form, however, DISE does not routinely determine the functional impact of anatomic and neuromuscular factors on airflow obstruction. The investigators will apply nasal pressure (CPAP) during DISE to generate pressure-flow and …

  • 04 Oct, 2022
  • 1 location
Syndrome Fibromyalgique en France : Place de l'évaluation et de la Prise en Charge Des Troubles du Sommeil (FIBOBS)

, divided into three categories (poor quality of sleep in general, sleep apnea syndrome, restless legs syndrome), using self-questionnaires in patients with Fibromyalgia Syndrome (FMS) consulting within a

chronic pain
  • 23 Oct, 2022
  • 41 locations