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Found 445 clinical trials
Comparative Efficacy of Cemiplimab to Historical Standard of Care in France (TOSCA)

Primary Objective: -Assess the effectiveness of cemiplimab versus other available systemic therapies in patients up to 2018 or say historical system organ class (SOC) with metastatic or locally advanced cutaneous Squamous Cell Carcinoma (CSCC) who are not candidates for curative surgery or curative radiation, on overall survival (OS). Secondary Objectives: …

  • 91 views
  • 10 Jun, 2022
  • 1 location
Study of Skin Tumors in Tuberous Sclerosis

examination by a dermatologist. Those with skin tumors will be asked to undergo biopsy (tissue removal) of up to eight lesions, under a local anesthetic, for research purposes. The biopsies will all be done

lymphangioleiomyomatosis
giant cell astrocytoma
genetic disorder
angiofibroma
astrocytoma
  • 15 views
  • 27 Jul, 2022
  • 1 location
Photographic Rhinometry Following Derm/Mohs Surgery for Skin Cancers

Dermatological surgeons and patients routinely notice alterations in nasal shape and size following surgery and reconstruction. There is no uniform approach to objectively measure these changes. Anthropometric measurements are routinely used in rhinoplasty to assess outcomes, but they are time consuming and have not been reported as being used by …

  • 0 views
  • 20 Apr, 2022
How Microbes and Metabolism May Predict Skin Cancer Immunotherapy Outcomes (MINING)

The purpose of this research study is to examine the relationship between the microbiota (microscopic organisms) in the gut and the activity of the immune system during skin cancer immunotherapy

skin cancer
cancer
  • 32 views
  • 31 Jan, 2022
  • 1 location
Pathological Characteristics of Basal Cell Carcinoma

A hospital based cross-sectional study was conducted from 2017 to February 2021. Clinical history, examination and histopathological variants were collected from medical files and pathology reports. Confirmation of pathology was done in all the patients visiting skin and plastic surgery department with suspected lesions.

  • 0 views
  • 21 Jul, 2022
  • 1 location
Non-Linear Imaging of Skin In Vivo

The overall objective of this study is to investigate the potential for Enspectra Investigational Device to display microscopic skin structure in people of different age, sex, race, and skin health.

Accepts healthy volunteers
  • 0 views
  • 20 Jun, 2022
Patient Reported Outcome Measures After Treatment of Skin Cancers on the Face

This study is to evaluate the psychological well-being in patients diagnosed with skin cancer (melanoma and Squamous Cell Carcinoma (SCC) in the face) at the time of diagnosis and after

carcinoma
squamous cell carcinoma
cancer
mohs surgery
  • 0 views
  • 10 Mar, 2022
  • 1 location
Applicability of a Cellular Resolution Full-field OCT Image System for Pigmented and Non-pigmented Skin Tumors

The incidence of skin cancer has been continuously increasing over the past decades und the number of non melanoma skin cancer is well as melanoma is still going to increase. Invasive biopsy and

skin lesion
skin diseases
skin tumor
melanoma skin
cancer
  • 0 views
  • 15 Nov, 2021
  • 1 location
Adjuvant Dabrafenib and Trametinib Treatment in Patients With Completely Resected High-risk Stage III Melanoma. (LEAD Melanoma)

Non-interventional (observational) cohort prospective real life study with primary and secondary data collection from patients on adjuvant treatment with dabrafenib + trametinib in patients with completely resected high-risk stage III (stage IIIA [lymph node > 1mm], IIIB, IIIC and IIID according to AJCC 8th edition) melanoma in Turkey.

trametinib
stage iii melanoma
melanoma skin
malignant melanoma of skin
immunomodulators
  • 0 views
  • 16 Mar, 2022
  • 8 locations
Peripheral T Cell Determinants of Response and Resistance to Pembrolizumab in Melanoma

This is a non-therapeutic study assessing peripheral T cell determinants of response and resistance to immunotherapy in patients with advanced melanoma.The hypothesis is that systemic T cells traffic into the tumor microenvironment (TME) can predict response and resistance to immunotherapy. These systemic tumor directed T cells can be defined by …

cancer
advanced melanoma
metastatic melanoma
pembrolizumab
measurable disease
  • 0 views
  • 24 Nov, 2021
  • 1 location