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Found 15 clinical trials
Recombinant Human Serum Albumin in Healthy Subjects

This trial adopts a single-center, randomized, double-blind, dose-escalation, placebo-controlled design to evaluate the safety, tolerability, pharmacokinetics, and efficacy of a single administration of recombinant human serum albumin in healthy subjects Kinetics and anti-drug antibody characteristics. Qualified healthy subjects (both male and female) were screened and enrolled to the four dose …

Accepts healthy volunteers
  • 0 views
  • 18 Jan, 2022
The Influence of Early and Continuous Exposure of Infants to Cow's Milk Formula on the Prevention of Milk Allergy

Cow's milk protein (CMP) allergy is one of the most common food allergies and potentially a fatal one. Early feeding with CMP has been considered in the past as a risk factor for development of CMP allergy in high risk infants. Although other studies argue with this assumption and suggest …

milk proteins
atopic dermatitis
atopy
cow's milk protein
milk allergy
  • 2 views
  • 27 Apr, 2021
  • 1 location
Assessment of Suppression of Cutaneous Allergic Responses and Pruritis by Topical Minocycline

Adults with known respiratory allergy/asthma with known skin test sensitization will undergo repeat skin prick testing at 4 areas of both arms (bilateral forearms, bilateral upper arms). Each

  • 0 views
  • 20 Oct, 2021
  • 1 location
Addiction HIV and Tuberculosis in Malaysian Criminal Justice Settings

(symptom screening, chest x-ray, tuberculin skin test, acid-fast bacilli smear, Gene Xpert, and sputum culture) to determine best practices for screening HIV+ and HIV- prisoners; b) A RCT of latent TB

isoniazid
opioid dependence
smear
naltrexone
rifapentine
  • 34 views
  • 20 Mar, 2021
  • 1 location
Study of RS1 Ocular Gene Transfer for X-linked Retinoschisis

exams. At visits 1-2, participants will have some or all of the following: Medical history Physical exam Blood and urine tests Tuberculosis skin

  • 62 views
  • 14 May, 2021
  • 1 location
An Open-Label Proof of Consent Study of Vorinostat for the Treatment of Mdoerate-to-Severe Crohn s Disease and Maintenance Therapy With Ustekinumab

Tests of blood, urine, and stool samples Heart test Questionnaires Tuberculosis skin test They may have a colonoscopy and lymphapheresis collection. These will be

corticosteroids
antibiotic therapy
tumor necrosis factor alpha
crohn's disease
certolizumab pegol
  • 53 views
  • 04 Nov, 2021
  • 1 location
Clinical Study of BCG Vaccine for Intradermal Injection

The study used a randomized, dose-escalation, blinded, placebo-controlled trial design. In this trial, 160 subjects were enrolled. The test vaccines are divided into four dose groups: dose group 1 (0.025mg / 0.1ml / person), dose group 2 (0.05mg / 0.1ml / person), dose group 3 (0.075mg / 0.1ml / person), …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Siltuximab in Schizophrenia

This study is a Phase 1 clinical trial to determine the safety, tolerability, and efficacy of Siltuximab (Sylvant) as an adjunct to antipsychotic medications in stable outpatients with schizophrenia. Siltuximab (structural formula C6450H9932N1688O2016S50) is a recombinant chimeric (human-murine) anti-human interleukin-6 (IL-6) monoclonal antibody. Siltuximab is formulated as a concentrate for …

antipsychotics
cancer
adjunctive treatment
schizoaffective disorder
psychotropic drugs
  • 93 views
  • 08 Aug, 2021
  • 1 location
PREVAIL VIII: A CoHOrt Clinical, Viral, and ImmuNOlogic Monitoring Study of People Living With Retroviral Infection in Liberia (HONOR)

to join a research substudy. This will be about tuberculosis (TB) testing in people with HIV. For this substudy, participants will have a TB skin test. A small amount of liquid will be injected under

immunodeficiency
AIDS
enzyme-linked immunosorbent assay
HIV Infection
drug use
  • 2 views
  • 19 Jan, 2022
  • 4 locations
Diagnosis and Treatment of Leishmania Infections

a splenic aspirate. For these procedures, a small tissue sample is withdrawn through a needle placed in the hipbone, liver or spleen, respectively. Some patients may also have a skin test for

punch biopsy
pentostam
apheresis
cutaneous leishmaniasis
blood tests
  • 21 views
  • 23 Jan, 2022
  • 1 location