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Found 12 clinical trials
A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a Cat

[S]) To determine the efficacy of REGN1908-1909, as compared to placebo, to inhibit a wheal-and-flare response to a skin prick test with cat allergen To assess the durability of

  • 3 views
  • 03 Jul, 2022
  • 84 locations
Low Dose Multi-Nut Oral Immunotherapy in Pre-schoolers With a Multi-Nut Allergy

The LMNOP trial will be a 2-armed, open-label, randomised controlled trial (RCT), 2:1. Over a period of 18 months, children in the Multi-Nut Oral Immunotherapy Treatment (OIT) Group (experimental arm) will undergo low dose OIT to two nuts they are allergic to. At this time, children in the Standard Care …

  • 0 views
  • 24 Nov, 2021
  • 1 location
The Feasibility of Systemic Reaction After Contact Exposure to the Allergenic Food in Children With Known Food Allergy

a few prospective studies that observed objectively the "reliability" of those subjective reports. The estimated chance for systemic allergic reaction due to skin prick test with fresh food is 0.008

Accepts healthy volunteers
  • 0 views
  • 02 Nov, 2021
  • 2 locations
Safety and Efficacy of Low-dose IL-2 in Birch Pollen Allergy (Rhinil-2)

Several studies have reported a deficit and/or a defect in regulatory T cells in allergic subjects, which can be correlated with the allergic responses, especially for respiratory allergies. Low-dose IL-2 (ld-IL2) specifically targets and activates regulatory T cells (Tregs), which are cells that regulate immune responses. Thus by stimulating Tregs, …

  • 0 views
  • 23 Mar, 2022
Clinical Study Using Biologics to Improve Multi OIT Outcomes

with a history of multiple food allergies of 2 to 3 different foods including peanut. Allergy will be confirmed by FA-specific IgE levels and positive skin prick test (SPT). Enrolled participants must

serum ige
dupilumab
biological factors
milk allergy
skin prick
  • 57 views
  • 01 Mar, 2022
  • 3 locations
The Effect of Per Oral Immunotherapy in Severe Milk Peanut and Egg Allergy in Adults

The aim is to analyse the results of per oral immunotherapy treatment in severe milk, peanut or egg allergy in adults. This is the second part of the oral immunotherapy study in adults at Skin and Allergy Hospital. The diagnosis of food allergy is verified with positive history, skin prick …

serum ige
milk allergy
egg allergy
allergen
prick skin
  • 57 views
  • 26 Jan, 2021
  • 1 location
Epigenetic Regulation of Exercise Induced Asthma

The purpose of this study is to investigate the micro ribonucleic acid (mRNA) profiles of patients with EIA without allergic sensitization and EIA with house dust mite sensitization compared to that of healthy controls.

Accepts healthy volunteers
  • 0 views
  • 26 Mar, 2022
  • 1 location
Behandling af Boern Med Foedevareallergi Med Omalizumab (Xolair)

Food allergy is a common disease in childhood affecting up to 8% of children in Westernized countries. About 30 percent of children with food allergies are allergic to more than one food, most often milk, egg, wheat, peanut and tree nut. Peanut and hazelnut are common triggers of severe and …

omalizumab
xolair
allergen
anaphylaxis
  • 0 views
  • 20 Sep, 2021
  • 1 location
Evaluate the Safety, Tolerability, Pharmacodynamics, and Efficacy of CNP-201 in Subjects Ages 16-35 With Peanut Allergy

This study is a two-part Phase 1b/2a First-in-Human (FIH) randomized, double-blind, placebo-controlled clinical trial to assess the safety, tolerability, pharmacodynamics, and efficacy of multiple ascending doses of CNP-201 in Part A, with the goal of identifying a safe and tolerable dose level to be evaluated further in a larger number …

  • 0 views
  • 06 Apr, 2022
  • 8 locations
Screening and Diagnosing Exercise-induced Bronchoconstriction in Recreational Young Athletes (12-18 y)

The purpose of this study is to validate the screening protocol to study risk factors of exercise-induced bronchoconstriction (EIB) obtained in our previous study in high-school elite athletes (NCT03587675), in recreational young athletes who perform intense physical exercise.

Accepts healthy volunteers
  • 0 views
  • 14 Nov, 2021
  • 1 location