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Found 57 clinical trials
Guselkumab in Active Psoriatic Arthritis Participants With Inadequate Response/Intolerance to One Prior Anti-TNF Alpha Agent (SOLSTICE)

The purpose of this study is to evaluate the efficacy of guselkumab treatment in participants with active psoriatic arthritis (PsA) and inadequate response (IR) and/or intolerance to a prior anti-tumor necrosis factor (TNF) by assessing the reduction in signs and symptoms of PsA.

rheumatoid nodules
tumor necrosis factor
polyarticular arthritis
tumour necrosis
psoriasis
  • 0 views
  • 09 Apr, 2023
  • 112 locations
Evaluation of Broadband Light Treatment for Pigmented Skin Lesions

Evaluation of safety and efficacy of Broadband light treatment

Accepts healthy volunteers
  • 0 views
  • 11 Apr, 2023
  • 1 location
Evaluation of Broadband Light Treatment Protocol for Pigmented Skin Lesions - A Comparative Study

Evaluation of Broadband Light Treatment Protocols for Pigmented Skin Lesions - A comparative study

Accepts healthy volunteers
  • 0 views
  • 09 Apr, 2023
  • 1 location
Predicting Inflammatory Skin Disease Response to IL-23 Blockade

This study examines the effect of IL-23 blockade with Tildrakizumab on the immune cells of psoriatic skin lesions.

  • 0 views
  • 16 Jun, 2022
  • 1 location
Augmenting Standard-of-care Treatment of Plaque Psoriasis by Neuromodulation

The human body responds to inflammation, such as psoriatic skin lesions, by activating the cholinergic anti-inflammatory pathway. In patients with plaque psoriasis, this pathway is not

  • 0 views
  • 12 May, 2022
  • 1 location
Skin Microbiome and Polymorphic Light Eruption

several hours after an intense UV exposure, most likely in spring or early summer, the formation of itchy skin lesions particularly at the upper arms and V-neck and neck is distinctive for PLE. It has

  • 0 views
  • 09 Aug, 2021
  • 1 location
Negative Pressure Ventilation in Paediatric Patients During Weaning (NEGWEAN)

Negative pressure ventilation (NPV) represent a unique form of noninvasive ventilation using negative pressure by specialized cuirass, that evolve negative pressure on the front size of chest and partially abdomen and facilitate the spontaneous breathing. The benefit of NPV beside noninvasive application, is the supreme tolerance of the patient (compared …

  • 0 views
  • 12 Apr, 2023
  • 1 location
Soluble Hyaluronic Acid Microneedle VS. Non-ablative Fractional Laser on Infraorbital Wrinkles.

This study is a prospective half-face controlled study, aiming to evaluate the therapeutic effects and adverse reactions of soluble hyaluronic acid microneedle and non-ablative fractional laser on infraorbital wrinkles and compare them.

Accepts healthy volunteers
  • 0 views
  • 05 Jul, 2022
  • 1 location
Returning Genetic Results on Arsenic Susceptibility

In recent years, returning genetic results to research participants has become a topic of debate, with a growing consensus that researchers should offer to return incidental findings and research results to participants. Currently, the research and debates surrounding return of results (ROR) have primarily taken place in high-income countries. Less …

Accepts healthy volunteers
  • 0 views
  • 03 Nov, 2021
  • 1 location
Non-invasive Photoacoustic Mesoscopic Imaging of Clinical Skin Inflammatory Disorders Coupled With Artificial Intelligence-assisted Scoring to Evaluate Disease Prognosis and Associated Metabolic Comorbidities

Inflammatory skin disorders are usually assessed by disease scoring system such as Scoring AD (SCORAD)/Eczema Area and Severity Index (EASI) and Psoriasis Area and Severity Index (PASI) for atopic eczema and psoriasis respectively. The current approach to score the severity of these inflammatory skin disorders is through clinical observations and …

Accepts healthy volunteers
plaque psoriasis
eczema
diabetes
dermatitis
  • 20 views
  • 11 Oct, 2022
  • 1 location