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Found 24 clinical trials
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A Study of Safety and Efficacy of MK-1986 (Tedizolid Phosphate) and Comparator in Participants From Birth to Less Than 12 Years of Age With Acute Bacterial Skin and Skin Structure Infections (MK-1986-018)

This study will evaluate the safety, tolerability, and efficacy of tedizolid phosphate (MK-1986) compared with comparator antibacterial agent in participants from birth to less than 12 years of age with acute bacterial skin and skin structure infections (ABSSSI).

  • 95 views
  • 01 Oct, 2021
  • 61 locations
None
The Efficacy and Safety of JAK Inhibitor in the Treatment of Anti-MDA5 Antibody-positive Dermatomyositis Patients

Anti-melanoma differentiation-associated gene5 (Anti-MDA5) antibody positive Dermatomyositis (DM) is a subtype of DM that is more frequent in East Asia, which is often exhibit skin lesion

  • 0 views
  • 31 Jul, 2021
  • 1 location
None
Improvement of Pigmented Skin Lesions in Patients With Mastocytosis After Performing 2 Sessions of Pigment Laser

Cutaneous mastocytosis can be isolated or associated with systemic involvement. Urticaria pigmentosa affects around 80 to 85% of adult patients with cutaneous mastocytosis. It is also frequently present in patients with mastocytosis associated with systemic involvement (80% of patients in our experience). This skin damage is one of the causes …

  • 0 views
  • 25 Jan, 2021
  • 1 location
None
Ultrasound in Diagnosing Patients With Skin Lesions

This trial studies the use of a novel non-invasive ultrasound technique in diagnosing patents with skin lesions. Diagnostic procedures, such as ultrasound, may be a less invasive way to check skin lesions for skin cancer and other skin disorders.

  • 0 views
  • 05 Jun, 2021
  • 1 location
None
Medical Device Based on Polarized Light for Cutaneous Lesions Visualization

Skin cancers represent a real public health issue. The diagnosis of pre-cancerous lesions thus is a priority. The diagnosis gold standard is based on the combination of clinical and histopathological examinations. Nevertheless, the clinical examination is not sufficiently effective, meaning that a biopsy has to be done for each suspected …

  • 0 views
  • 21 Sep, 2021
  • 1 location
None
Skin Imaging to Inform Laser Treatments

have 510k clearance and are being used as per their approved indications in this study. The choice of laser type is based on the skin lesion and is recommended by the physician, and the subjects who

skin lesion
skin disorder
Accepts healthy volunteers
  • 119 views
  • 07 Oct, 2021
  • 1 location
None
Study of TVEC in Patients With Cutaneous Squamous Cell Cancer

This is single arm a Phase 2, single center study of talimogene laherparepvec (TVEC) to treat low risk cutaneous squamous cell carcinomas (cSCC).

cancer
neutrophil count
carcinoma
platelet count
anticoagulants
  • 11 views
  • 30 Jun, 2021
  • 1 location
None
Aspirin as an add-on Treatment of Refractory Epilepsy in Tuberous Sclerosis Complex

There had been much evidence in aspirin controlling tumorous conditions conducted by basic researches, especially through mammilian target of rapamycin (mTOR) pathway. The investigator observed efficacy of aspirin in the treatment of tuberous sclerosis complex (TSC) in one child who got Kawasaki disease and in the addition four TSC patients …

sirolimus
antiepileptics
aspirin
antiepileptic drugs
vagus nerve stimulation
  • 69 views
  • 25 Jan, 2021
  • 1 location
None
A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

This research is being done to study the safety of implanting and retrieving a microdevice that releases up to 19 drugs directly within a cancerous lesion as a possible tool to evaluate the effectiveness of several approved cancer drugs against cutaneous T cell lymphoma and peripheral T cell lymphoma

peripheral t-cell lymphoma
vorinostat
neutrophil count
corticosteroids
antineoplastic agents
  • 0 views
  • 05 Jul, 2021
None
Cicaderma Efficacy vs Standard Care of Sites in Preventing Radiodermatitis in Non-metastatic Breast Cancer Patients

Phase III, prospective, interventional, multicentric, comparative, randomized, open study with 2 parallel arms, evaluating the efficacy of Cicaderma ointment vs standard management of each site in preventing the onset of grade > 2 radiodermatitis according to the National Cancer Institute - Common Terminology Criteria for Adverse Events-Version (NCI-CTCAE-V5)

  • 0 views
  • 14 Feb, 2021
  • 3 locations