Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 362 clinical trials
None
Topical Tranexamic Acid Use on Granulating Wounds Following Mohs Micrographic Surgery

tranexamic acid when applied topically to the skin wound after surgery.

  • 0 views
  • 05 Oct, 2021
  • 1 location
None
The Treatment of Type I Open Fractures in Pediatrics

Open fractures are frequently encountered in orthopaedics. Treatment usually calls for a formal, operative procedure in which the bone is exposed, foreign tissue is debrided and the wound is irrigated. While this is the current standard of care, not all open fractures are equal. In retrospective studies, centers are reporting …

  • 14 views
  • 09 Sep, 2021
  • 1 location
None
The SAFE Trial. Sterile Amniotic Fluid Filtrate Epidural Injection.

There is a large population of patients with lumbosacral radicular pain due to spinal stenosis who do not respond to physical therapy or oral medication management, yet wish to avoid spinal surgery or are simply not candidates due to medical co-morbidity. Given the natural history of lumbar spinal stenosis, these …

  • 2 views
  • 23 Oct, 2021
  • 1 location
None
Study of Safety and Efficacy of Novel Immunotherapy Combinations in Patients With Triple Negative Breast Cancer (TNBC).

This is a Phase Ib, open label, dose escalation study of spartalizumab + LAG525 in combination with NIR178, capmatinib, MCS110, or canakinumab, followed by a dose expansion in adult patients with advanced or metastatic TNBC. During the dose-escalation part of each treatment arm, patients will be treated with fixed doses …

estrogen receptor
progesterone
progesterone receptor
adjuvant chemotherapy
measurable disease
  • 44 views
  • 05 Aug, 2021
  • 13 locations
None
Safety and Efficacy of Midline and PICC

The purpose of this study is to assess the non-inferiority for safety and efficacy of using Midline in comparison with PICC for intravenous therapy that do not require a central catheter.

  • 0 views
  • 31 Aug, 2021
  • 2 locations
None
Immunogenicity and Safety Study of a Quadrivalent Meningococcal Conjugate Vaccine Administered Concomitantly With Routine Pediatric Vaccines in Healthy Infants and Toddlers

The primary objective of this study is to demonstrate the non-inferiority of the vaccine seroresponse to meningococcal serogroups A, C, Y, and W following administration of 2 doses of MenACYW conjugate vaccine compared to 2 doses of MENVEO when given concomitantly with routine pediatric vaccines to infants and toddlers 6 …

Accepts healthy volunteers
  • 420 views
  • 29 Oct, 2021
  • 110 locations
None
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC

Phase III Study of Capivasertib + Paclitaxel versus Placebo + Paclitaxel as First line Treatment for Patients with Locally Advanced or Metastatic Triple-negative Breast Cancer (TNBC)

cancer
formalin-fixed paraffin-embedded
measurable disease
breast cancer
paclitaxel
  • 1388 views
  • 24 Nov, 2021
  • 335 locations
None
Motor Language Learning

This project pursues the validation of an innovative strategy to boost language learning, based on the benefits derived from sensorimotor training. The common belief of a rigid brain structure in adult life had to be reconsidered during the last decade. After training, local increase in cerebral cortex volume and thickness, …

  • 42 views
  • 23 Jan, 2021
  • 1 location
None
Toripalimab in Combination With Nab-Paclitaxel For Patients With Metastatic or Recurrent Triple-Negative Breast Cancer (TNBC) With or Without Systemic Treatment

This multicenter, randomized, double-blind study will evaluate the efficacy and safety of Toripalimab (JS001) combined with nab-paclitaxel compared with placebo combined with nab-paclitaxel for first/second line treatment of metastatic or recurrent triple-negative breast cancer (TNBC).

cancer
HER2
human epidermal growth factor
growth factor
mammogram
  • 28 views
  • 24 Jan, 2021
  • 79 locations
None
A Study of Atezolizumab Plus Nab-Paclitaxel in the Treatment of Unresectable Locally Advanced or Metastatic PD-L1-Positive Triple-Negative Breast Cancer

Study MO39874 is an open-label, phase IIIb, single arm, multicenter study conducted in participants with unresectable locally advanced or metastatic PD-L1-positive Triple-Negative Breast Cancer (TNBC) who have not received chemotherapy for their unresectable locally advanced or metastatic disease.

cancer
HER2
serum pregnancy test
mammogram
triple-negative breast cancer
  • 147 views
  • 30 Nov, 2021
  • 164 locations