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Found 100 clinical trials
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IONIS TCH Biomarker Study

IONIS TCH Biomarker Study: The TCH Ionis Biomarker is a study for males only and is looking for a marker in the body that can show us if a person has too much or too little MECP2 in their brain. This is important, as future genetic therapies may change the …

  • 0 views
  • 25 Jan, 2021
featured
A Washington University research study seeks female participants.

A Washington University research study seeks female participants.

  • 160 views
  • 23 Nov, 2020
  • 1 location
Genomic Responses of Human Immune and Non-Immune Cells to Glucocorticoids

hours. Participants will have medical history, physical exam, and 3 blood draws. Participants will have a skin biopsy. An injection will numb the skin on one arm. Then a tool will remove

  • 0 views
  • 28 Feb, 2021
  • 1 location
Characterization of Skin Immunity to Aedes Aegypti Saliva in Dengue-endemic Participants in Cambodia

will have 1 skin biopsy. Participants will have a final visit about 2 weeks later. They will have a physical exam and blood tests. During the study, participants will be asked to take

  • 0 views
  • 03 Mar, 2021
  • 1 location
Secukinumab Therapy for the Treatment of Moderate to Severe Plaque Psoriasis With Response Monitoring Using Optical Coherence Tomography (OCT).

This is a phase IV, single-center, open label, single arm study in which a group of 30 subjects with moderate to severe plaque psoriasis will receive secukinumab therapy. Non-invasive imaging with optical coherence tomography (OCT) will be used to monitor the resolution of psoriatic plaques with treatment in comparison to …

secukinumab therapy
tubal ligation
psoriasis
tuberculin purified protein derivative
oophorectomy
  • 22 views
  • 26 Jan, 2021
  • 1 location
NIAGEN and Persistent Chemotherapy-Induced Peripheral Neuropathy

The purpose of this randomized, double-blind, placebo-controlled, parallel group phase II trial is to determine whether nicotinamide riboside (NIAGEN, NR) can ameliorate persistent peripheral neuropathy in cancer survivors who have completed chemotherapy with taxane or platinum-complex compounds between 1 and 12 months earlier.

taxane
peripheral neuropathy
cancer
ovarian cancer
paclitaxel
  • 2 views
  • 25 Jan, 2021
  • 1 location
Evaluating Safety & Efficacy of Apremilast in the Treatment of Cutaneous Disease in Patients With Recalcitrant Dermatomyositis

With limited treatment options available for dermatomyositis, the investigators hypothesize that apremilast, a phosphodiesterase-4 (PDE-4) inhibitor, is a safe and efficacious add-on treatment in patients with refractory cutaneous dermatomyositis. The study will investigate the efficacy, safety and toxicity of apremilast given at 30 mg twice daily to patients with refractory …

  • 2 views
  • 18 Feb, 2021
  • 1 location
Predictive Clinical and Biological Parameters in Acute Leukemia Myelodysplastic Syndromes and Myeloproliferative Disorders-HEMATO-BIO-IPC-2013-015

diagnosis and/or complete remission and/or relapse tumor samples: marrow aspiration, blood sampling. non-tumor samples: skin biopsy, buccal swab . from 650

acute leukemia
bone marrow procedure
leukemia
cancer
myelodysplastic syndromes
  • 13 views
  • 22 Jan, 2021
  • 1 location
IVIg for Small Fiber Neuropathy With Autoantibodies TS-HDS and FGFR3

hypothesize that individuals with auto-antibodies targeting neuronal antigens (TS-HDS and FGFR3) and confirmed evidence of small fiber neuropathy (by skin biopsy analysis of intra-epidermal nerve fiber

skin biopsy
  • 367 views
  • 24 Jan, 2021
  • 1 location
Chronic Cough and Small Fiber Neuropathy

assessment will be concluded with a skin biopsy to evaluate small fiber neuropathy. The aim of the study is to compare the proportion of small fiber neuropathy between diabetic patients with chronic cough

  • 0 views
  • 26 Jan, 2021
  • 1 location