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Found 103 clinical trials
Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures at High Risk of Infection: TOBRA

The overall objective is to compare the effect of Vancomycin and Tobramycin powder combined (treatment) to Vancomycin powder (control) in the reduction of post-fixation infections of tibial plateau and tibial pilon fractures at high risk of infection (collectively considered the "study injuries").

  • 11 Jul, 2021
  • 1 location
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT - A Multicenter Randomized Control Trial

The proposed study is a multi-center, prospective randomized controlled trial comparing current standard of care treatment to the SEXTANT treatment protocol in patients with Type III open fractures of the tibia and IIIB fractures of the ankle and hindfoot.

  • 18 Sep, 2022
  • 1 location
Prospective Study on Cesarean Wound Outcomes

surgical site infection after application of silver plated dressings versus standard Telfa dressings. Investigators will also assess the cosmetic appearance of the cesarean section scar at the

  • 07 Nov, 2020
  • 1 location
The Efficacy of Chlorhexidine Gluconate Gel Dressing in Preventing Surgical Drain Site Infection

This study aims to evaluate if the application of chlorhexidine gluconate dressing on surgical drain sites can decrease drain site infection vs the standard of care (dry, sterile gauze).

  • 17 Sep, 2022
  • 1 location
Negative Pressure Incision Management System in Infrainguinal Vascular Surgery

Negative pressure wound therapy (NPWT) has been used in treating postoperative SSI with encouraging results and is now an accepted element in the arsenal of tools for treating these complications. The concept of applying NPWT to closed surgical wounds as a preventive measure is relatively new but draws on the …

  • 26 Apr, 2022
  • 1 location
Hydrocolloid Dressing for Catheter Exit Site Care in Peritoneal Dialysis Patients

The study aims to examine the use of hydrocolloid dressing for catheter exit-site care in peritoneal dialysis patients. It is a pilot study, and participants will be randomized to either receiving weekly hydrocolloid dressing or daily topical gentamicin cream for exit-site care in peritoneal dialysis patients.

  • 23 May, 2022
  • 1 location
Mechanical Bowel Preparation and Oral Antibiotics Before Rectal Cancer Surgery (PREPACOL2)

reduction of postoperative surgical site infection rate, as compared to mechanical bowel preparation alone Our hypothesis is that a preoperative colonic preparation including a combination of mechanical

  • 27 May, 2022
  • 1 location
Robotic Versus Open Primary Ventral Hernia Repair (Robovent)

one month up to 25%. To date three techniques are used. Open ventral hernia repair (OVHR) is associated with a high risk of surgical site infection, wound dehiscence, and hematoma, but is the

repair of ventral hernia
wound infection
postoperative hernia
umbilical hernia
  • 25 Jul, 2022
  • 1 location
Preoperative Preparation With Lugol Solution in Patients With Graves-Basedow Disease. (LIGRADIS)

: hypoparathyroidism, paralysis of the recurrent laryngeal nerve, postoperative hematoma, surgical site infection or death. Debit for surgical drains. Postoperative hospital long of stay.

postoperative hematoma
  • 28 Feb, 2022
  • 19 locations
Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge (RICART)

Adult patients who are regularly scheduled to undergo a right hemicolectomy via a minimally invasive approach (robotic or laparoscopic) with the creation of an anastomosis.

  • 16 May, 2022
  • 1 location