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Found 140 clinical trials
Sirolimus for Cowden Syndrome With Colon Polyposis

reduction in the number of colon polyps with the use of the medication sirolimus for a very short time period. This study is investigating sirolimus and its effect on the number of colon polyps in patients

  • 0 views
  • 23 Jan, 2021
  • 1 location
Topical Sirolimus in Cutaneous Lymphatic Malformations

CMLMs are disappointing, and their management is challenging. Sirolimus is an inhibitor of mammalian target of rapamycin (mTOR), a serine/threonine protein kinase involved in cell growth and

  • 0 views
  • 27 Jan, 2021
  • 15 locations
Efficacy and Safety of Sirolimus to Vascular Anomalies

To evaluate the safety and efficacy of Sirolimus in complicated vascular anomalies in Chinese children

  • 0 views
  • 26 Jan, 2021
  • 1 location
A Futility Trial of Sirolimus in Multiple System Atrophy

Single-center, randomized, placebo-controlled, phase-II, futility clinical trial to determine if oral sirolimus is of sufficient promise to slow disease progression in MSA, prior to embarking on

sirolimus 2 mg
sirolimus
  • 531 views
  • 25 Jan, 2021
  • 1 location
Study of Sirolimus in Patients With Advanced Pancreatic Cancer

of energy metabolism, cell growth, angiogenesis and other cellular biological processes.Rapamycin (sirolimus) is a selective inhibitor of mTOR kinase, which can inhibit the activation and

folfirinox
gemcitabine
solid tumour
metastasis
fluorouracil
  • 3 views
  • 22 Jan, 2021
Sirolimus Use in Angioplasty for Vascular Access Extension

Dialysis patients presenting for angioplasty intervention for graft failure will be randomized to receive either Sirolimus or not receive Sirolimus (standard of care) to assess the time from

platelet count
dialysis
sirolimus
  • 42 views
  • 25 Jan, 2021
  • 2 locations
Sirolimus in Previously Treated Idiopathic Multicentric Castleman Disease

The purpose of this study is to understand the impact of sirolimus on idiopathic multicentric Castleman disease.

  • 0 views
  • 24 Jan, 2021
  • 1 location
TReAtmeNt of Small Coronary Vessels: MagicTouch Sirolimus Coated Balloon

sirolimus coated balloon (Concept Medical) and SeQuent Please paclitaxel coated balloon (B Braun). The objective of the study is to compare angiographic outcomes of Magic TouchTM sirolimus coated balloon

stable angina
acute coronary syndrome
troponin
paclitaxel
sirolimus
  • 0 views
  • 26 Jan, 2021
  • 5 locations
Safety and Efficacy of Low-dose Sirolimus to Kaposiform Hemangioendothelioma

to evaluate the safety and efficacy of Low-dose sirolimus in Kaposiform Hemangioendothelioma in Chinese children by a prospective, randomized open trial.

kasabach-merritt phenomenon
hemangioendotheliomas
  • 0 views
  • 25 Jan, 2021
  • 1 location
Testing SIROLIMUS in Beta-thalassemia Transfusion Dependent Patients (THALA-RAP)

, and on pharmacokinetics and pharmacovigilance already assessed. Rapamycin (as Sirolimus) is an immunosuppressant agent, approved by the FDA for acute rejection prevention in renal transplant

  • 0 views
  • 03 Feb, 2021
  • 4 locations