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Found 140 clinical trials
Sirolimus-Based Immunosuppression Therapy in OLT for Patients With HCC Exceeding Milan Criteria

The purpose of this study is to evaluate the influence of sirolimus on outcome after OLT for HCC exceeding Milan criteria.

vascular invasion
  • 1 views
  • 07 Nov, 2020
  • 1 location
Sirolimus (Rapamune ) for Relapse Prevention in People With Severe Aplastic Anemia Responsive to Immunosuppressive Therapy

marrow from making these cells. The treatment cyclosporine leads to better blood counts. But when this treatment is stopped, the disease may return in 1 in 3 people. The drug sirolimus may help by

immunosuppressant
blood test
sirolimus
cyclosporine
reticulocyte count
  • 7 views
  • 07 Mar, 2021
  • 1 location
Cyclophosphamide and Sirolimus for the Treatment of Metastatic RAI-refractory Differentiated Thyroid Cancer

This study will be a non-randomized pilot trial using Cyclophosphamide and Sirolimus for the treatment of metastatic differentiated thyroid cancer. Patients will be treated with Sirolimus 4 mg

  • 6 views
  • 24 Jan, 2021
  • 1 location
SAVE Trial - Use of the Selution Sirolimus Eluting Balloon for Dysfunctional AV accEss Treatment Indications

Prospective dual-center single-blinded randomized controlled trial (RCT) investigating the safety and feasibility of the SELUTION SLR (Sustained Limus Release) 018 drug eluting balloon (DEB) for the treatment of failed AV fistula in renal dialysis patients. Patients will be randomised to either SELUTION SLR or POBA.

  • 0 views
  • 03 Feb, 2021
  • 2 locations
Efficacy and Safety of Different Concentrations of Sirolimus in the Treatment of Kaposiform Hemangioendothelioma.

The purpose of this study is to compare the efficacy and safety of different concentration gradients of sirolimus in the treatment of Kaposiform hemangioendothelioma.

  • 0 views
  • 07 Mar, 2021
  • 1 location
A First-in-Man Study to Evaluate the Feasibility and Safety of Sirolimus-eluting Iron Bioresorbable Coronary Scaffold System

The study is a pilot clinical trial for Sirolimus-eluting Iron Bioresorbable Coronary Scaffold SystemIBS. The main purpose of this study is to evaluate the feasibility, preliminary safety and

  • 5 views
  • 22 Jan, 2021
  • 2 locations
Treatment of In-Stent Restenosis 2 Study

The aim of this study is to compare the efficacy of sirolimus-eluting balloon catheters (SEB) and iopromide-coated paclutaxel-eluting balloon catheters (PEB) in the treatment of bare metal (BMS

sirolimus
in stent restenosis
paclitaxel
  • 2 views
  • 25 Feb, 2021
  • 1 location
Allograft for Sickle Cell Disease and Thalassemia

ablation. If the graft is rejected, the patient will reconstitute autologous marrow function. We will use a combination of low dose irradiation, Alemtuzumab (Campath), and sirolimus. Peripheral

  • 28 views
  • 18 Feb, 2021
  • 1 location
Arteriovenous Fistulae: Drug-eluting Balloon Angioplasty

Dysfunctions such as tight stenosis or thrombosis in haemodialysis vascular accesses are the leading cause of hospitalisationand morbidity in chronic haemodialysis patients incurring significant related costs estimated at over one billion dollars in the USA. Dysfunctions of these vascular accesses are generally treated by conventional angioplasty as this is the …

  • 1 views
  • 22 Jan, 2021
  • 11 locations
CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation

The primary objective of the trial is to evaluate efficacy and safety of delayed introduction (up to 30 days post-transplantation in patients without signs of acute rejection that had received an aIL-2 induction and MMF) of either cyclosporine or everolimus versus a 5-day delay of cyclosporine in combination with MMF.

everolimus
immunosuppression
cyclosporine
liver transplant
  • 12 views
  • 08 Nov, 2020
  • 1 location