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Found 295 clinical trials
Mobile Integrated Health in Heart Failure

The purpose of this study is to compare how two different types of care after a hospitalization reduce hospital readmissions and symptom burden. The two types of care are a Transitions of Care Coordinator and Mobile Integrated Health. In the Transitions of Care Coordinator group, participants will receive a phone …

heart failure
  • 0 views
  • 06 Jun, 2022
  • 2 locations
Outcomes Mandate National Integration With Cannabis as Medicine (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

covid-19
brimonidine tartrate ophthalmic solution
Accepts healthy volunteers
medical marijuana
disease or disorder
  • 15131 views
  • 13 Jun, 2022
  • 16 locations
PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST) (PROTEST)

This is a pilot study, phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI).

subarachnoid hemorrhage
severe traumatic brain injury
traumatic brain injury
  • 119 views
  • 16 Feb, 2022
  • 10 locations
A Trial to Assess the Effect of Transfusion Strategies on Fatigability Levels After Hospital Discharge (EToF)

This study is a randomized controlled trial in which hospitalized patients with anemia are randomized to receive transfusion at: a) Hb<9g/dL (liberal transfusion strategy), or b) Hb<7g/dL (restrictive transfusion strategy). We are measuring self-reported fatigability, fatigue, and activity levels at randomization and 7 days post hospital discharge in both trial …

anemia
red blood cell transfusion
  • 0 views
  • 05 Jun, 2022
  • 1 location
The Swedish BioFINDER 2 Study (BioFINDER2)

The Swedish BioFINDER 2 study is a new study that will launch in 2017 and extends the previous cohorts of BioFINDER 1 study (www.biofinder.se). BioFINDER 1 is used e.g. to characterize the role of beta-amyloid pathology in early diagnosis of Alzheimer's disease (AD) using amyloid-PET (18F-Flutemetamol) and A analysis in …

amyloid
neurodegenerative diseases
alzheimer's disease
dementia
mild cognitive impairment
  • 178 views
  • 25 Feb, 2022
  • 1 location
Sickle Cell Disease and CardiovAscular Risk - Red Cell Exchange Trial (SCD-CARRE) (SCD-CARRE)

The SCD-CARRE trial is a Phase 3, prospective, randomized, multicenter, controlled, parallel two-arm study aimed to determine if automated exchange blood transfusion and standard of care

hydroxyurea
thalassemia
hemoglobin s
blood transfusion
sickle hemoglobin
  • 24 views
  • 18 Sep, 2022
  • 17 locations
Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using Plerixafor

administration of plerixafor in pediatric and young adult patients with sickle cell disease (SCD). To estimate the number of CD34+ cells/kg of body weight that can be collected with peripheral

conjugated bilirubin
hydroxyurea
apheresis
blood transfusion
plerixafor
  • 0 views
  • 15 Sep, 2022
  • 1 location
Cutaneous Hydration Assessment in SCD

status and its potential to guide hydration therapy in patients with sickle cell disease (SCD).

thalassemia
  • 0 views
  • 26 Apr, 2022
Sleep Apnea in Sickle Cell Disease (DREPAPNEE)

pathophysiological mechanisms are scarce. OSA is one of the most common conditions responsible for hemoglobin desaturation. The nocturnal hemoglobin desaturation occurring in some sickle cell disease (SCD) patients

hemoglobin s
vaso-occlusive crisis
blood transfusion
sickle hemoglobin
sickle cell trait
  • 10 views
  • 01 Feb, 2022
  • 3 locations
Evaluation of Safety and Efficacy of CTX001 in Pediatric Participants With Severe Sickle Cell Disease (SCD)

This is a single-dose, open-label study in pediatric participants with severe SCD and hydroxyurea (HU) failure or intolerance. The study will evaluate the safety and efficacy of autologous

busulfan
hydroxyurea
  • 0 views
  • 13 Jun, 2022
  • 1 location