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Found 227 clinical trials
Validating Pain Scales in Children and Young Adults

that can lead to cancer. Objectives To study the effectiveness of pain rating scales given to children and adults with Sickle Cell Disease (SCD

sarcoma
solid tumor
malignant solid tumor
cancer
  • 33 views
  • 28 Jun, 2022
  • 1 location
An Observational Long-term Safety and Efficacy Follow-up Study After Ex-vivo Gene Therapy With BIVV003 in Severe Sickle Cell Disease (SCD) and ST-400 in Transfusion-dependent Beta-thalassemia (TDT) With Autologous Hematopoietic Stem Cell Transplant

Primary Objectives: -Long-term safety of BIVV003 in participants with severe sickle cell disease (SCD) and ST- 400 in participants with transfusion-dependent beta-thalassemia (TDT)

  • 0 views
  • 23 May, 2022
  • 1 location
An Observational Long-term Safety and Efficacy Follow-up Study After Ex-vivo Gene Therapy With BIVV003 in Severe Sickle Cell Disease (SCD) and ST-400 in Transfusion-dependent Beta-thalassemia (TDT) With Autologous Hematopoietic Stem Cell Transplant

Primary Objectives: -Long-term safety of BIVV003 in participants with severe sickle cell disease (SCD) and ST- 400 in participants with transfusion-dependent beta-thalassemia (TDT)

  • 108 views
  • 13 May, 2022
  • 1 location
Discarded Bone Marrow for Hematology Research

editing strategies as potentially curative therapy for hemoglobinopathies (e.g. sickle cell disease (SCD) and β-thalassemia). To develop a drug treatment strategy which elevates the expression of

  • 0 views
  • 17 Jun, 2022
  • 1 location
ERYthrocyte Morphology Using Flow Imaging on ImageSTREAM Cytometer (ERYSTREAM)

anemias for example, it allows the recognition of therapeutic emergencies such as sickle cell disease crisis, malaria-induced hemolysis and thrombotic microangiopathy, the latter being characterized by

  • 0 views
  • 22 Apr, 2022
  • 1 location
Precision Exercise in Children With Malignant Hemopathies

In the early years of life and during adolescence, physical activity is crucial for good development of motor skills. It is even more so for those children and young people who are forced to undergo anti-cancer therapies and therefore undergo long periods of hospitalization (often bedridden) and prolonged periods of …

hematologic disorder
cancer
lymphoma
leukemia
Accepts healthy volunteers
  • 0 views
  • 06 Oct, 2021
Perceptions of LARC Among AYA With Chronic Illness (LARC)

The investigators aim to perform a qualitative study exploring attitudes and perceived barriers to Long Acting Reversible Contraception (LARC), both implants and IUDs, among adolescent and young adults (AYA) with chronic illness at CHLA. While the literature examining barriers to LARC uptake is growing, its focus has been on older …

  • 0 views
  • 10 May, 2022
  • 1 location