Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 300 clinical trials
Fludarabine Phosphate, Cyclophosphamide, Total Body Irradiation, and Donor Stem Cell Transplant in Treating Patients With Blood Cancer

This phase II trial studies how well fludarabine phosphate, cyclophosphamide, total body irradiation, and donor stem cell transplant work in treating patients with blood cancer. Drugs used in chemotherapy, such as fludarabine phosphate and cyclophosphamide, work in different ways to stop the growth of cancer cells, either by killing the …

thrombasthenia
myeloid leukemia
lymphoid leukemia
polycythemia vera
lymphocytic leukemia
  • 135 views
  • 30 Apr, 2022
  • 1 location
New Patient-specific Functional Assessment of the Anomalous Aortic Origin of Coronary Arteries.

Anomalous Aortic Origin of the Coronary Arteries (AAOCA) is a rare congenital disease that may cause sudden death in young subjects. Frequently the first and only presentation is with an acute event (such as myocardial infarction or sudden cardiac deaths) during physical effort. Not only symptoms are often absent, but …

intravascular ultrasound
MRI
infarct
ischemia
myocardial infarction
  • 0 views
  • 23 Dec, 2021
  • 1 location
Preventing Cognitive Decline

The study aims to understand the mechanisms and training effects of evidence-based body-mind training on improving cognitive performance and preventing cognitive decline.

Accepts healthy volunteers
  • 0 views
  • 22 Jul, 2022
  • 1 location
Preventive VT Substrate Ablation in Ischemic Heart Disease (PREVENT-VT)

The investigators hypothesize that preventive VT substrate ablation in patients with chronic ICM, previously selected based on imaging criteria (BZC mass) for their likely high arrhythmic risk, is safe and effective in preventing clinical VT events.

heart disease
MRI
catheter ablation
  • 0 views
  • 02 Jun, 2022
  • 1 location
Kardia Mobile for Detecting Arrhythmias in Children

The objective of this project is to evaluate the Kardia Mobile capability of detecting arrhythmic events in children with history of palpitation and or syncope. We will compare this approach with the standard approach of clinical follow-up plus 24-hour Holter ECG monitoring in terms of acceptability and ability to identify …

holter monitor
electrocardiographic monitoring
diagnostic procedure
syncope
electrocardiogram
  • 0 views
  • 08 Dec, 2021
  • 1 location
Biomarker-based Multidisciplinary Team (Bio-MDT) Approach to Personalized Microbial-targeted Treatment of Pouchitis and Crohn's Disease

Crohn's disease (CD) and ulcerative colitis (UC) are chronic inflammatory bowel diseases (IBD) currently affecting over 5 million patients globally, mostly young adults. These conditions are often debilitating, disabling and may markedly affect patient's quality of life. Despite important advances in research, the pathogenesis of IBD remains obscure, the incidence-rising, …

enteropathy
ulcerative colitis
colectomy
crohn's disease
antibiotics
  • 0 views
  • 25 Jan, 2021
  • 1 location
Acute GVHD Suppression Using Costimulation Blockade to Expand Non-malignant Transplant (ASCENT)

The ASCENT Trial is a single arm, multi-center, phase II study. The primary objective is to determine the rejection-free, severe graft-versus-host disease (GVHD)-free survival in pediatric patients with serious non-malignant hematologic diseases (NMHD) undergoing unrelated donor (URD) hematopoietic stem cell transplantation (HSCT) with abatacept added to conventional GVHD prophylaxis. The …

chronic graft versus host disease
granulocyte colony stimulating factor
anemia
tacrolimus
acute graft-versus-host disease
  • 4 views
  • 04 Feb, 2022
  • 6 locations
A Study to Determine Iatrogenic Hyperinsulinemia's Contribution to Insulin Resistance and Endothelial Dysfunction in Type 1 Diabetes

The investigators will test the hypothesis that reducing insulin doses using a low carbohydrate diet (LCD) will be associated with with improved insulin sensitivity (Aim 1) and blood vessel health (Aim 2).

  • 0 views
  • 27 Sep, 2021
  • 2 locations
Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT (HSCT+RIC)

The objective of this study is to evaluate the efficacy of using a reduced-intensity condition (RIC) regimen with umbilical cord blood transplant (UCBT), double cord UCBT, matched unrelated donor (MUD) bone marrow transplant (BMT) or peripheral blood stem cell transplant (PBSCT) in patients with non-malignant disorders that are amenable to …

  • 22 views
  • 28 May, 2022
  • 1 location
Prevention of Inflammatory Bowel Diseases in Persons at Risk The PIONIR (Preventing IBD Onset in Individuals at Risk) Trial (PIONIR)

The goal of this study is to explore in a cross over randomized controlled trial, the ability of the Tasty&Healthy dietary intervention (NCT04239248) to alter the parameters associated with future risk of developing Chron's disease (CD) using subjects identified in the Genetic Environmental Microbiome (GEM) Study as having a high-risk …

enteropathy
ulceration
faecal calprotectin
Accepts healthy volunteers
capsule endoscopy
  • 0 views
  • 25 Mar, 2022
  • 1 location