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Found 300 clinical trials
Effect of Exercise on Biomarkers in SCT

This study measures the effect of exercise on a variety of biomarkers in blood and urine selected to evaluate the physiological pathways of hemolysis, myolysis, thrombosis, inflammation, and renal function in subjects with sickle cell trait. These pathways have been shown to be associated with adverse events in athletes and …

Accepts healthy volunteers
hemolysis
sickle cell trait
  • 0 views
  • 22 Mar, 2022
  • 1 location
Effects of Experimental Sleep Disturbances on Receptor Function of Study Drug

The overall goal of this project is to determine whether common sleep disturbance patterns, sleep continuity disturbance (SCD) and Sleep Fragmentation (SF), alter cerebral study drug receptor

total sleep time
benzodiazepines
analgesics
sleep disturbances
Accepts healthy volunteers
  • 202 views
  • 20 Nov, 2021
  • 1 location
Pre-transplant Immunosuppression and Donor Stem Cell Transplant for the Treatment of Severe Hemoglobinopathies

This clinical trial studies the effect of pre-transplant immunosuppression (PTIS) and donor stem cell transplant in treating patients with severe blood diseases (hemoglobinopathies). PTIS helps prepare the body for the transplant and lowers the risk of developing graft versus host disease (GVHD). Hematopoietic cells are found in the bone marrow …

hemoglobinopathy
acute chest syndrome
anti-thymocyte globulin
priapism
stroke
  • 0 views
  • 29 Jun, 2022
  • 1 location
Low Dose Aspirin for Preventing Intrauterine Growth Restriction and Preeclampsia in Sickle Cell Pregnancy (PIPSICKLE) (PIPSICKLE)

Pregnancy in sickle cell disease (SCD) is fraught with many complications including preeclampsia (PE) and intrauterine growth restriction (IUGR). Previously, the investigators found an

aspirin
Accepts healthy volunteers
fetal growth retardation
vasoconstrictor
  • 0 views
  • 05 Mar, 2022
  • 13 locations
Modulation Effects of Baduanjin Exercise on Subjective Cognitive Decline

brain morphometry in individuals with subjective cognitive decline (SCD). The results obtained will provide novel insights for improving the prevention of age-related cognitive decline and Alzheimer's

memory impairment
mental deterioration
mini-mental state examination
dementia
cognitive assessment
  • 0 views
  • 07 Jul, 2021
  • 1 location
Cognitive Behavioral Therapy and Real-Time Pain Management Intervention for Sickle Cell Via Mobile Applications (CaRISMA)

The investigators are conducting a comparative effectiveness trial among adult patients with sickle cell disease (SCD) who report chronic pain (N = 350), randomized to receive either mobile

analgesia
analgesics
chronic pain
opioid
cognitive behavioral therapy
  • 54 views
  • 11 May, 2022
  • 6 locations
Single-Blind Study of STAT-205 in Mild COVID-19

age or with any one or more of certain medical conditions including: cancer, COPD, cardiovascular disease, immunocompromised state resulting from solid organ transplant, obesity, sickle cell disease

  • 0 views
  • 01 Jan, 2022
  • 1 location
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies

This is a study to collect the outcomes of stem cell transplantation for patients with hematologic diseases other than cancer.

total body irradiation
hemoglobinopathy
anti-thymocyte globulin
alemtuzumab
cell transplantation
  • 231 views
  • 22 Apr, 2022
  • 1 location
NWT-03 and Brain Function

cognitive decline (SCD) the effects of a 36-weeks NWT-03 intervention on (1) cognitive performance using a neurophysiological test battery, and (2) cerebral blood flow, as quantified by the current non

  • 0 views
  • 20 Jun, 2021
  • 1 location
An Intervention to Reduce Risk Factors for Adolescent Pregnancy

Investigators will assess the preliminary effects of Girls Invest, an innovative savings intervention that aims to reduce economic, social, and health behavior risks associated with disproportionately high rates of pregnancy among US Latina adolescents. Girls Invest involves a multidisciplinary conceptual model adapting the most effective prevention strategies from the disciplines …

Accepts healthy volunteers
  • 0 views
  • 27 May, 2022
  • 1 location