Found 227 clinical trials
Sickle Cell Disease Study: Own Your Health, Share Your Story with PicnicHealth
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- 736 views
- 27 Oct, 2022
- 1 location
- Online study
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease
Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the
- 83 views
- 22 Dec, 2020
- 1 location
A Study of FT-4202 in Adults and Adolescents With Sickle Cell Disease (Hibiscus Study)
This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of FT-4202 and test how well FT-4202 works compared to placebo to improve the amount of hemoglobin in the blood and to reduce the number of vaso-occlusive crises (times when the blood vessels become blocked …
- 22 views
- 22 Dec, 2021
- 29 locations
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease
sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of the red blood cell. Differences in the PKLR gene, called genetic
- 63 views
- 22 Dec, 2020
- 1 location
H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.
H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.
- 910 views
- 08 Nov, 2020
- 1 location
Sickle Cell Single/Multiple Dose Study
A randomized, placebo-controlled, double blind, single ascending and multiple ascending dose study to assess the safety in healthy volunteers and sickle cell disease. Facility is in Miami, Florida
- 15 views
- 25 Jan, 2021
- 1 location
Covid-19 Pill Study | A0017
This is a study for the treatment of COVID-19 for those who may be immunocompromised. The treatment is administered orally by pill.
- 21 views
- 31 Mar, 2023
- 1 location
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) (PROTECT-ICD)
MI. Following a MI patients are at high risk of sudden cardiac death (SCD). The risk is highest in the first 40 days; however, current guidelines exclude patients from receiving an ICD during
- 267 views
- 15 May, 2022
- 26 locations
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)
The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.
- 114 views
- 12 Sep, 2023
- 252 locations
The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia (VoxSCAN)
Voxelotor is a new drug for adolescents and adults with sickle cell disease that improves hemoglobin levels and reduces the incidence of worsening anemia. However, it is unclear whether this
- 0 views
- 07 Oct, 2022
- 2 locations