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Found 254 clinical trials
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Sickle Cell Disease Study

Study of Oral medication in Patients with Sickle Cell Disease.

sickle cell disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
featured
Sickle Cell Food Study

An Open Label Food Study to Assess the Safety, Tolerability and Physiological Effects of an Amino Acid Food Product in Subjects with Sickle Cell Disease  

  • 32 views
  • 25 Jan, 2021
  • 1 location
featured
Clinical, Electrocardiographic, and Cardiac Magnetic Resonance Imaging Risk Factors Associated with Ventricular Tachyarrhythmias in Nonischemic Cardiomyopathy (MARVEN Study)

; hazard ratio 0.65; p=0.08) and a subgroup analysis of the SCD-HeFT trial [2] (792 patients; hazard ratio = 0.73; p=0.06) showed a non-significant but clinically meaningful reduction in mortality, and

heart study
  • 350 views
  • 24 Nov, 2020
  • 1 location
featured
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the

sickle cell disease
cell transplantation
stroke
red blood cell disorder
  • 57 views
  • 22 Dec, 2020
  • 1 location
featured
Sickle Cell Single/Multiple Dose Study

A randomized, placebo-controlled, double blind, single ascending and multiple ascending dose study to assess the safety in healthy volunteers and sickle cell disease. Facility is in Miami, Florida

  • 9 views
  • 25 Jan, 2021
  • 1 location
featured
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of the red blood cell. Differences in the PKLR gene, called genetic

sickle cell disease
sickle cell anemia
red blood cell disorder
  • 48 views
  • 22 Dec, 2020
  • 1 location
featured
H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

  • 888 views
  • 08 Nov, 2020
  • 1 location
featured
A Washington University research study seeks participants with heart failure.

A Washington University research study seeks participants with heart failure.

  • 122 views
  • 25 Mar, 2021
  • 1 location
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

MI. Following a MI patients are at high risk of sudden cardiac death (SCD). The risk is highest in the first 40 days; however, current guidelines exclude patients from receiving an ICD during

  • 104 views
  • 23 Jan, 2021
  • 36 locations
Allograft for Sickle Cell Disease and Thalassemia

anemias. The patient cohort to be studied: Those patients with severe sickle cell disease and thalassemia who have risk factors for high mortality and morbidity related to their disease

  • 28 views
  • 18 Feb, 2021
  • 1 location