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Found 375 clinical trials
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Solid Tumors Malignancies

This clinical trial is evaluating a drug called BT8009 alone and in combination with nivolumab in participants with advanced solid tumors associated with Nectin-4 expression or in participants with advanced solid tumor malignancies having renal insufficiency. The main goals of this study are to: Find the recommended dose of BT8009 …

cancer of the ovary
triple negative breast cancer
lung carcinoma
lung cancer
targeted therapy
  • 22 Mar, 2022
  • 16 locations
MGC018 With or Without MGA012 in Advanced Solid Tumors

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics (PK) pharmacodynamics and preliminary antitumor activity of MGC018 administered alone and in combination with MGA012 in patients with advanced solid tumors.

systemic therapy
chemotherapy regimen
hormone therapy
measurable disease
  • 12 Mar, 2022
  • 19 locations
Safety and Efficacy of KY1044 and Atezolizumab in Advanced Cancer

A Phase 1/2, open label, multi-center study to evaluate the safety, efficacy and tolerability of KY1044 as single agent and in combination with anti-PD-L1 (atezolizumab) in adult patients with selected advanced malignancies, who are ineligible for or there are no available therapies known to confer a clinical benefit for their …

triple negative breast cancer
lung carcinoma
lung cancer
measurable disease
  • 09 Jun, 2022
  • 10 locations
A Safety Study of SEA-TGT (SGN-TGT) in Advanced Cancer

This trial will look at a drug called SEA-TGT (also known as SGN-TGT) to find out whether it is safe for patients with solid tumors and lymphomas. It will study SEA-TGT to find out what its side effects are. A side effect is anything the drug does besides treating cancer. …

measurable disease
stage iv non-small cell lung cancer
salvage therapy
diffuse large b-cell lymphoma
stem cell transplantation
  • 29 May, 2022
  • 30 locations
INCB106385 Alone or in Combination With Immunotherapy in Advanced Solid Tumors

This is a multicenter, open-label, dose-escalation/dose-expansion Phase 1 clinical study to investigate the safety, tolerability, PK profile, pharmacodynamics, and preliminary clinical efficacy of INCB106385 when given as monotherapy or in combination with INCMGA00012 in participants with selected CD8 T-cell-positive advanced solid tumors including SCCHN, NSCLC, ovarian cancer, CRPC, TNBC, bladder …

bladder tumor
measurable disease
cancer of the ovary
  • 17 Jun, 2022
  • 18 locations
Study of SO-C101 and SO-C101 in Combination With Pembro in Adult Patients With Advanced/Metastatic Solid Tumors

A multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of SO-C101 as monotherapy and in combination with pembrolizumab in patients with selected advanced/metastatic solid tumors

serum pregnancy test
chemotherapy regimen
biological factors
  • 30 Apr, 2022
  • 7 locations
Sensory Processing and Musculoskeletal Shoulder Pain

The development of chronic pain is a common complication in shoulder pain conditions. Half of these type of patients exhibit persistent pain even after a period of six to twelve months from the

Accepts healthy volunteers
  • 08 Jun, 2022
  • 1 location
Multimodal Treatment for Hemiplegic Shoulder Pain

Hemiplegic shoulder pain (HSP) affects up to 60% of moderate to severely impaired stroke survivors. HSP is associated with poor rehabilitation outcomes, including interference with activities of

localized pain
pain relief
mini-mental state examination
  • 25 Feb, 2022
  • 1 location
Development of an Electronic Suit to Reduce Hemiplegic Shoulder Pain

and clinical experience, this study will explore the potential value of the EXOPULSE Mollii suit-method in the management of post stroke shoulder pain. The overall aim of this study is to test and

  • 08 Sep, 2021
  • 1 location
Web-based Instrument Intervention for Individuals With Shoulder Pain

Introduction: Shoulder pain is a condition of high prevalence in the general population. Studies indicate that physiotherapeutic treatment with exercise is effective in reducing pain and

  • 26 Nov, 2021
  • 1 location