Found 31 clinical trials
Healthy Volunteer Short Chain Fatty Acid Study
The purpose of this study is to evaluate the production of short chain fatty acids (fatty acids are part of your diet) in stool through the measurement of fecal inulin after a one-time ingestion
- 35 views
- 10 Mar, 2022
- 1 location
Role of Gut Microbiota in the Pathophysiology of Aseptic Abscesses (ABSCESSBIOT)
and saliva, short chain fatty acids on stool and lymphocyte study on blood.
- 0 views
- 11 Oct, 2022
- 12 locations
Pilot Clinical Trial on the Effects of Dietary Fibres on the Gut Microbiome and Metabolic Profiles in a Transgenerational Cohort
Dietary fibres are complex carbohydrates present in fruit, vegetables, grains, and beans which are broken down into smaller molecules (short-chain fatty acids) in the colon by the gut microbiota
- 0 views
- 16 Oct, 2022
- 1 location
Effect of Prebiotics on Hyperuricemia
Hyperuricemia is a major risk factor for many chronic diseases. Recently, dysbiosis of gut microbiota has been reported to play an important role in the pathogenesis of Hyperuricemia. Animal studies have demonstrated that administration of prebiotics help delay the progression of Hyperuricemia through several mechanisms. This trial aims to examine …
- 0 views
- 02 Jun, 2022
- 2 locations
Microbiota Transplant Therapy for Pulmonary Arterial Hypertension: Early Safety and Feasibility Study
This pilot clinical trial will evaluate the initial safety and feasibility of intestinal microbiota transplantation (IMT) in patients with pulmonary arterial hypertension (PAH). This trial will inform development of future trials in treatment of PAH. Active drug in capsule form composed of freeze-dried, encapsulated intestinal microbiota from healthy donors will …
- 4 views
- 08 Dec, 2021
- 1 location
Dietary Fiber Effects on the Microbiome and Satiety
Strong evidence supports the association between high fiber (HiFi) diets (e.g. legumes, nuts, vegetables) and a reduced risk for chronic conditions such as cardiovascular disease (CVD), type 2 diabetes and some forms of cancer. However, the current U.S. average consumption of dietary fiber of 17g/day is significantly below the recommendation …
- 0 views
- 28 Oct, 2021
- 1 location
The Influence of Physical Activity on the Gut Microbiome of Pre-Diabetic Adults
exercise (MWE) for 30-45 min 3 times/week alters the gut microbiome, serum short chain fatty acids, and the cardiometabolic profile, body weight, and body composition of individuals 30-64 years old who
- 0 views
- 06 Apr, 2023
- 1 location
Salt and HMB Study
-diversity and gut microbiota-derived short-chain fatty acids (SCFAs). However, the leucine/α-KIC/HMB metabolism pathway has never been targeted in human studies. To establish causality, I propose a double
- 0 views
- 07 Oct, 2022
- 1 location
Predictive Value of Hydrogen/Methane Lactose Breath Testing on the Therapeutic Effect of Lactose-free Diet in Moderate to Severe ROME IV IBS.
lactose will eventually reach the colon, resulting in fermentation from colonic bacteria with production of different compounds such as short chain fatty acids, carbon dioxide, H2 and methane (Catanzaro
- 0 views
- 04 Oct, 2022
- 1 location
Prebiotic vs Probiotic in Multiple Sclerosis (MS)
This is a randomized crossover-designed study to explore the immunologic effects of Prebiotics, as opposed to direct supplementation with beneficial bacteria (Probiotics) in the immune system of patients with MS and Clinically Isolated Syndrome (CIS). Eligible patients will take 6 weeks of two different supplements - Prebiotics and Probiotics. Participants …
- 4 views
- 10 Apr, 2023
- 2 locations