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Found 66 clinical trials
Tezepelumab COPD Exacerbation Study (COURSE)

Obstructive Pulmonary Disease (COPD)

copd exacerbation
bronchodilator
ct scan
severe chronic obstructive pulmonary disease
  • 258 views
  • 25 May, 2022
  • 79 locations
A Study Comparing Efficacy, Safety and Tolerability of the Fixed Dose Triple Combination CHF 5993 With the Fixed Dose Dual Combination CHF 1535 in Subjects With COPD (TRITON)

The purpose of this study is to compare CHF 5993 with CHF 1535 in improving lung function, reducing moderate and severe COPD exacerbations, and other clinical efficacy and safety outcomes in the

  • 0 views
  • 08 Jun, 2022
Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE) (RELIANCE)

A multi-center, randomized, 36-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at …

COPD
pulmonary disease
muscarinic antagonist
corticosteroids
daliresp
  • 265 views
  • 11 Apr, 2022
  • 30 locations
myAirvo 3 (High Flow Nasal Therapy; HFNT) for COPD Patients in the Home

year and up to two years in 642 GOLD Grade D, Stages III-IV patients with moderate to very severe COPD at risk for moderate and severe exacerbations with a prior history of severe exacerbation

  • 0 views
  • 11 Mar, 2022
  • 1 location
A Phase II, Randomized, Double-blind, Placebo-controlled Study to Assess MEDI3506 in Participants With COPD and Chronic Bronchitis (FRONTIER-4)

This is a research study to determine the efficacy and safety of investigational drug MEDI3506 for the treatment of adult subjects with Chronic Obstructive Pulmonary Disease and Chronic Bronchitis.

pulmonary disease
corticosteroids
COPD
antibiotics
body mass index
  • 82 views
  • 03 Jun, 2022
  • 89 locations
Multidisciplinary Management of Severe COPD

Chronic Obstructive Pulmonary Disease (COPD) is a common chronic disease that is characterized by persistent airflow limitation, that is due to airway and/or alveolar abnormalities usually caused by significant exposure to noxious particles or gases, particularly cigarette smoking. Latest updates of the Global Burden of Disease emphasize the dramatic size …

  • 0 views
  • 21 Mar, 2022
  • 1 location
Multidimensional Individualized Nutritional Therapy for Individuals With Severe COPD (MINDNUT)

improve quality of life for individuals with severe COPD. 120 individuals are recruited from the outpatient clinic at Nordsjællands Hospital in Denmark to a randomized controlled trial with two

  • 0 views
  • 21 Mar, 2022
  • 0 views
  • 12 Mar, 2022
  • 3 locations
Exploration of the VOLATOLOM in the Stable Severe COPD (Chronic Obstructive Pulmonary Disease) (VOC-BPCO)

This is a prospective interventional study to determine whether the profile of volatile organic compounds (VOCs) present in exhaled air (VOLATOLOM) is reproducible in stable severe COPD (Chronic

  • 0 views
  • 22 Mar, 2022
  • 1 location
Efficacy of an Advanced Auto-titrating NIV in COPD

Patients with chronic obstructive pulmonary disease (COPD) can eventually progress to respiratory failure, where they cannot adequately exchange oxygen and carbon dioxide, leading to worsening breathlessness, frequent hospitalisations and death. Non-invasive ventilation (NIV) is a ventilator therapy that is used in COPD patients who suffer from respiratory failure. Studies have …

  • 0 views
  • 17 Jun, 2021
  • 1 location