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Found 338 clinical trials
Featured trial
Depression Research Study

The Shoreline study is evaluating an investigational oral medication to see if it reduces symptoms of moderate-to-severe depression.  

depressed mood
severe depression
  • 462 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS).

A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants With Cognitive Impairment Associated With Schizophrenia (CIAS).  

major depressive episode
major depressive disorder
depression
depressed
  • 78 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Depression - Treatment Resistant

Still feeling symptoms of Depression after having taken a prescription Antidepressant?  If so, participating in our medical research study of an investigational drug may be an option for you.

depressive episode
depressed mood
antidepressants
depressive symptoms
  • 596 views
  • 05 Apr, 2021
  • 1 location
Featured trial
Depression

Depression...It interferes with the ability to work, eat, sleep and enjoy life.  If you are experiencing symptoms of depression, a clinical research study may be your next step.  

depressed mood
depressive symptoms
  • 574 views
  • 05 Apr, 2021
  • 1 location
Featured trial
Apathy and Reward Systems in Alzheimer’s Disease

This study is looking for people over the age of 65 who have either early stage Alzheimer’s/mild cognitive impairment or depression. The study is interested in examining cognition and brain characteristics, and their relationship with Alzheimer’s and depression.

mild cognitive impairment
depressed mood
cognitive impairment
psychiatric disorder
  • 17 views
  • 07 Dec, 2020
  • 1 location
Featured trial
A Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexipiprazole as Adjunctive Therapy in the Maintenance of Adults With Major Depressive Disorder

A study to compare the efficacy of brexpiprazole to placebo as adjunctive therapy to antidepressant therapy for the maintenance treatment in adults with major depressive disorder.  

antidepressant therapy
depressive disorder
  • 90 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Phase 2a Randomized, Double-blind, Placebo-Controlled, Parallel-Group, Multi-center Study Investigating the Efficacy, Safety, Tolerability and Pharmacokinetics of JNJ-XXX in Subjects with Major Depressive Disorder

A study to evaluate the efficacy of JNJ-XXX compared to placebo when administered as adjunctive treatment in subjects with MDD partially responsive to SSRI/SNRI treatment in terms of reduction of symptoms of depression.  

selective serotonin reuptake inhibitors
depressed mood
depressive symptoms
  • 59 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Double-Blind, Placebo-Controlled Study of Cariprazine as an Adjunct to Antidepressants in the Treatment of Patients With Major Depressive Disorder Who Have Had an Indadequate Response to Antidepressants Alone

A study to evaluate the efficacy, safety, and tolerability of cariprazine compared with placebo as an adjunctive treatment to ongoing antidepressant therapy in patients with major depressive disorder who have had an inadequate response to antidepressants alone.  

antidepressant therapy
depressive disorder
antidepressants
  • 94 views
  • 23 Nov, 2020
  • 1 location
Featured trial
A Research Study is being conducted to evaluate an investigational product to be used for the treatment of Major Depressive Disorder (or MDD) in women. Qualified participants receive study-related care, and exams at no charge.

A Research Study is being conducted to evaluate an investigational product to be used for the treatment of Major Depressive Disorder (or MDD) in women. Qualified participants receive study-related care, and exams at no charge.

  • 924 views
  • 08 Nov, 2020
  • 1 location
Featured trial
A Phase 2a, Randomized, Placebo-Controlled Clinical Study to Evaluate the Efficacy and Safety of MK-1942 Added to Stable Antidepressant Therapy in Participants With Treatment-Resistant Depression

Merck Sharp & Dohme Corp. is conducting this trial to test the investigational drug MK-1942 in people with treatment-resistant depression. The purpose of this trial is to test the safety, efficacy, and tolerability of the trial drug, MK-1942.Additionally, the sponsor is interested to see if subjects who get MK-1942 have …

  • 1 views
  • 06 Apr, 2021
  • 1 location