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Found 22 clinical trials
Lenalidomide in Anti-MAG Neuropathy: Phase 1b Study

this drug is effective in this subset of patients, using preselected, specifically tailored outcome measures that encompass quality of life, neurologic function, serum protein levels, and focused

  • 66 views
  • 26 Jan, 2021
  • 2 locations
Effects of Nutritional Preconditioning on the Patient's Outcomes After Surgery

serum protein markers and their ratios in order to correlate them with ASPEN's criteria for nutritional status quantification. In Summary, three discrete tools including ASPEN's criteria, indirect

  • 0 views
  • 08 Jul, 2021
  • 1 location
Bendamustine Rituximab and Acalabrutinib in Waldenstrom's Macroglobulinemia

This is a multi-centre, open label, single-arm, phase II clinical trial in untreated patients with Waldenstrom's Macroglobulinemia. Symptomatic, previously untreated patients will receive SOC bendamustine and rituximab for 6 28-day cycles. Bendamustine will be given intravenously at 90 mg/m2 on days 1 and 2 of each cycle. Rituximab will be …

corticosteroids
lymphoma
monoclonal protein
bendamustine
rituximab
  • 0 views
  • 01 Aug, 2021
  • 5 locations
Intracranial Activity of AZD9291 (TAGRISSO) in Advanced EGFRm NSCLC Patients With Asymptomatic Brain Metastasessor

Patients will receive AZD9291 at a dose of 80 mg once daily. Intracranial response will be assessed with brain MRI scan, systemic evaluation will be done by PET-CT (Positron Emission Tomography-Computed Tomography) scan. In case of isolated CNS progression which may or may not be accompanied by asymptomatic systemic progression, …

ct scan
afatinib
hysterectomy
total bilirubin
brain metastases
  • 41 views
  • 25 Jan, 2021
  • 2 locations
The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients

The incidence of malnutrition in patients with severe neurological diseases is approximately 37%, among which hypoproteinemia is a common manifestation. It has been confirmed that serum albumin level is closely related to severity and mortality for patients. Protein is the basic component of tissue cells in the body, which plays …

casein
hypoproteinemia
nutritional support
malnutrition
tube feeding
  • 0 views
  • 19 Feb, 2021
  • 1 location
Lactobacillus Rhamnosus GG (ATCC 53103) in Mild-moderately Active UC Patients

This study is a randomized double-blind clinical trial that intends to evaluate the efficacy and safety of LGG administration at two different doses, for 1 month, in ulcerative colitis (UC) patients with mild-moderate disease activity in therapy with oral mesalamine. Efficacy of therapy will be evaluated by clinical (Clinical Mayo …

  • 1 views
  • 30 Apr, 2021
  • 1 location
Detection of Early Lung Cancer by Serum Protein Expression Profiling

Promising new technology exists to examine small proteins that are shed by cancers into the blood stream. The purpose of this study is to see if there are differences in the proteins and protein levels in blood from individuals with early stage lung cancer compared to healthy adults.

chemoradiotherapy
  • 173 views
  • 07 Nov, 2020
  • 1 location
Evaluation of New Biomarker-based Approaches for Improving the Diagnosis of Childhood Tuberculous Meningitis

The rapid diagnosis of tuberculosis (TB) in children remains a serious challenge owing to limitations in the existing diagnostic tests. TB meningitis (TBM), an extrapulmonary form of TB, is the most severe manifestation of paediatric TB. TBM results in high morbidity and mortality in children, despite the availability of chemotherapy, …

  • 0 views
  • 27 Jan, 2021
  • 1 location
Pan-canceR Early-Stage deteCtion by lIquid Biopsy tEchNique projecT

PRESCIENT is a multi-center, prospective observational study aimed to detect cancers early by combined assays for serum protein markers and cell-free DNA (cfDNA) methylation markers. Blood RNA

primary cancer
  • 0 views
  • 10 Jun, 2021
  • 1 location
Case-Control Study of the Glycotest HCC Panel vs AFP for the Detection of Early-stage Hepatocellular Carcinoma

Clinical guidelines (AASLD) recommend the use of abdominal ultrasound (US) for surveillance testing for the early detection of Hepatocellular Carcinoma (HCC). The serum protein biomarker alpha

carcinoma
alpha fetoprotein
cirrhosis
ct scan
hypertension
  • 1 views
  • 26 Jan, 2021
  • 18 locations