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Found 17 clinical trials
ExtraCorporeal Membrane Oxygenation in the Therapy of Cardiogenic Shock

surgery). Implantation of other mechanical support devices including ECMO in the primary conservative group is allowed in the case of shock progression with rise of serum lactate by 3 mmol/L in comparison

systolic blood pressure
norepinephrine
inotropic agent
vasopressor
serum lactate
  • 6 views
  • 19 Sep, 2021
  • 6 locations
Safety and Usability of the LUMENA Non-invasive Ventilation Mask

Evaluation of the safety and efficacy of using the Lumena mask, compared to commercially-available, commonly used Oro-nasal masks.

assisted ventilation
non-invasive ventilation
  • 0 views
  • 11 Aug, 2022
Rituximab and Lenalidomide vs Rituximab Alone as Maintenance After R-chemoterapy for Relapsed/Refractory FL Patients (FIL_RENOIR12)

A randomized phase III multicenter trial assessing efficacy and toxicity of a combination of Rituximab and Lenalidomide (R2) vs Rituximab alone as maintenance after chemoimmunotherapy with Rituximab-chemotherapy (R-CHT) for relapsed/refractory FL patients not eligible for autologous transplantation (ASCT)

tumor burden
rituximab
bendamustine
neutrophil count
lenalidomide
  • 58 views
  • 11 Aug, 2022
  • 28 locations
Treatment Strategies in Colorectal Cancer Patients With Initially Unresectable Liver-only Metastases (CAIRO5)

Colorectal cancer patients with initially unresectable liver-only metastases may be cured after downsizing of metastases by neoadjuvant systemic therapy. However, the optimal neoadjuvant induction regimen has not been defined, and no consensus exist on criteria for resectability. In this study colorectal cancer patients with initially unresectable liver-only metastases, as prospectively …

neutrophil count
ct scan
primary tumor
folfox regimen
cancer
  • 249 views
  • 07 Apr, 2022
  • 50 locations
Preventive Therapy of Postoperative Intra-abdominal Infection Based on Serum Lactate Changes

intra-abdominal infection. According to the previous retrospective study, changes of serum lactate level on postoperative day1 could predict the incidence rate of postoperative intra-abdominal infection

  • 0 views
  • 03 Oct, 2021
  • 1 location
Anesthesia in Patients With Mitochondrial Disease

This pilot study is a prospective, randomized clinical trial to evaluate the effect of anesthesia in the mitochondrial dysfunction patient.

  • 26 views
  • 25 Jan, 2022
  • 1 location
Mitochondrial Complex I Dysfunction in PWS

Prader-Willi Syndrome (PWS) is characterized by profound infantile hypotonia, growth delay, cognitive impairment, muscle weakness and exercise intolerance. Studies have suggested that a defect in energy metabolism, yet to be clarified, may be involved in its pathogenesis. Many PWS patients have received Coenzyme Q10, but the rationale for this and …

  • 0 views
  • 10 Aug, 2022
  • 1 location
Assessment of ECMO in Acute Myocardial Infarction Cardiogenic Shock (ANCHOR)

Data from case series and large retrospective trials suggest that the early treatment of cardiogenic shock AMI patients with the association of VA-ECMO and IABP may significantly decrease mortality, which is still unacceptably high nowadays (40-50% at 30 days). An important benefit for the patients randomized to the ECMO arm …

  • 0 views
  • 10 Aug, 2022
  • 1 location
Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive care unit (ICU) mortality in patients with septic shock and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) remains high and approximates 50-60%. Sepsis is the leading etiology for AKI and CRRT …

hemodiafiltration
renal replacement therapy
  • 0 views
  • 20 Aug, 2021
  • 1 location
A Phase 2 Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients

A Phase 2, Multi-Center, Randomized, Placebo-Controlled, Dose-Finding Study Evaluating Efficacy, Safety and Tolerability of Different Doses and Regimens of Allocetra-OTS for the Treatment of Organ Failure in Adult Sepsis Patients

antibiotics
hematuria
pneumonia
organ failure
sepsis
  • 0 views
  • 15 Jun, 2022
  • 15 locations