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Found 16 clinical trials
NMDA Modulation in Major Depressive Disorder

Most of the current antidepressants for major depressive disorder (MDD) are based upon the monoamine hypothesis which cannot fully explain the etiology of depression. NMDA hypofunction has been implicated in the pathophysiology of depression. Therefore, this study will examine the efficacy and safety as well as cognitive function improvement of …

  • 0 views
  • 25 Nov, 2021
  • 1 location
Predicting SSRI Efficacy in Veterans With PTSD (SSRI)

This is a research study to examine the effectiveness of a brief screening method that may predict which people with posttraumatic stress disorder (PTSD) or depression are most likely to show a positive response to selective serotonin reuptake inhibitor (SSRI) medications. Participants will be recruited over approximately 3.25 years, until …

sertraline
depression
selective serotonin reuptake inhibitors
  • 2 views
  • 14 Apr, 2022
  • 1 location
Predicting Treatment Response in Patients With OCD

This study consists of a naturalistic follow-up of subjects with Obsessive-Compulsive Disorder (OCD) that have participated in a global study investigating brain signatures of OCD funded by the National Institutes of Mental Health (RO1MH113250), with the following participant sites: the US (Columbia University, PI: Helen Blair Simpson), Brazil (University of …

serotonin reuptake inhibitors
psychotropic drugs
  • 127 views
  • 03 Jun, 2022
  • 2 locations
Personalized Sertraline Dosing in Patients With Depression (PsyCise-S)

The aims of this study are to: Determine the proportion of participants who are underdosed or overdosed under recommended dosing regimen of sertraline for the depression treatment

  • 0 views
  • 22 Mar, 2022
  • 2 locations
Pharmacokinetics and Pharmacodynamics of Oral Sertraline Before and After Bariatric Surgery (ANTILOP)

Volunteers with a prescription of oral sertraline who have been scheduled to bariatric surgery in either Norrkping/Sweden or Lindesberg/Sweden will be asked to participate in a observational

sertraline
  • 2 views
  • 28 Feb, 2022
  • 2 locations
First choIce Antidepressants: General Practitioner's Treatment Approach in the Czech Republic (FIAT)

serotonin reuptake inhibitors (SSRI), e.g. citalopram, escitalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, in depression with anxiety and insomnia is preferable trazodone and in severer disorders

  • 0 views
  • 10 Apr, 2022