Found 13 clinical trials
A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder
A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder
- 1451 views
- 25 Mar, 2021
- 1 location
Comparison of Antidepressant Augmentation With Amantadine vs Pramipexole vs Quetiapine in Treatment Resistant Depression (APQ-TRD)
depression clinically diagnosed as TRD, who are currently on Sertraline treatment (dose range = 100-200 mg/day). At baseline, Hamilton Depression Scale (HAM-D 21 item) will be administered to determine the
- 0 views
- 29 Aug, 2023
- 1 location
Pragmatic Trial of Obsessive-compulsive Disorder (Proceed)
This study includes a sequenced clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffective，and to provide strong evidence for clinical practice and international guidelines for Obsessive-Compulsive Disorder treatments.
- 5 views
- 07 Oct, 2022
- 1 location
Sequenced Treatment Alternatives to Relieve Adolescent Depression (STAR-AD) (STAR-AD)
This project aims to investigate the effectiveness of existing common antidepressants and to provide new evidence for depressed children and adolescents who are not responding to their first treatment.
- 0 views
- 19 Aug, 2023
- 1 location
Sequenced Treatment Effectiveness for Posttraumatic Stress (STEPS)
Individuals with PTSD are more likely to engage in unhealthy behaviors such as tobacco use, drug use, alcohol misuse, and have high rates of morbidity/mortality. PTSD negatively impacts marriages, educational attainment, and occupational functioning. Some patients with PTSD can be successfully referred to specialty mental health clinics, but most patients …
- 294 views
- 11 Apr, 2023
- 13 locations
Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive Disorder
To verify that sertraline combined with fluvoxamine is superior to sertraline combined with aripiprazole
- 0 views
- 25 Jul, 2021
- 1 location
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders. (EV-SoPRANO)
A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.
- 0 views
- 16 Sep, 2023
- 1 location
Establishing Multimodal Brain Biomarkers for Treatment Selection in Depression (Re-EMBARC)
The purpose of the study is to identify brain biomarkers and characteristics that predict individual responses to treatment of major depression with the antidepressant drug sertraline (tradename
- 0 views
- 09 Sep, 2023
- 1 location
Neural Markers of Treatment Mechanisms and Prediction of Treatment Outcomes in Social Anxiety
(CBT). Adults in the SAD group who do not respond enough to group CBT may be offered the opportunity to complete an additional 12 weeks of individual CBT while receiving SSRI medication (sertraline
- 0 views
- 26 Aug, 2023
Partners in Caring for Anxious Youth
SSRI (either fluoxetine, sertraline, or escitalopram). CBT in PCAY will be 6 months in duration and include more family involvement, and more exposure opportunities than past trials. The 6-month acute
- 0 views
- 10 Sep, 2021
- 3 locations
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