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Found 17 clinical trials
Featured trial
A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder

A Phase 2, Multicenter, Randomized, Double-blind, Placebo- and Active-controlled Trial of Brexpiprazole (1 - 3 mg/day) as Monotherapy or as Combination Therapy in the Treatment of Adults with Post-traumatic Stress Disorder

  • 1451 views
  • 25 Mar, 2021
  • 1 location
Brexpiprazole as Combination Therapy With Sertraline in Treatment of Adults With PTSD

This will be a 12-week, multicenter, randomized, double-blind trial evaluating the efficacy, safety, and tolerability of brexpiprazole + sertraline combination treatment in adult subjects with

sertraline
  • 39 views
  • 28 Jul, 2022
  • 1 location
Brexpiprazole as Combination Therapy With Sertraline in the Treatment of Adults With Post-traumatic Stress Disorder

This will be a 12-week, multicenter, randomized, double-blind trial evaluating the efficacy, safety, and tolerability of fixed-dose brexpiprazole + sertraline combination treatment in adult

sertraline
  • 36 views
  • 24 Jul, 2022
  • 1 location
A Pragmatic Trial of Pharmacotherapy Options Following Unsatisfactory Initial Treatment in OCD (Proceed)

This study includes a sequenced clinical trial in order to assess the efficacy of several switching or augment strategies when initial treatment is ineffective,and to provide strong evidence for clinical practice and international guidelines for Obsessive-Compulsive Disorder treatments.

sertraline
fluvoxamine
psychotherapy
treatment regimen
memantine
  • 5 views
  • 15 Sep, 2022
  • 1 location
Sequenced Treatment Effectiveness for Posttraumatic Stress

Individuals with PTSD are more likely to engage in unhealthy behaviors such as tobacco use, drug use, alcohol misuse, and have high rates of morbidity/mortality. PTSD negatively impacts marriages, educational attainment, and occupational functioning. Some patients with PTSD can be successfully referred to specialty mental health clinics, but most patients …

selective serotonin reuptake inhibitors
antidepressants
venlafaxine
fluoxetine
exposure therapy
  • 199 views
  • 05 Jul, 2021
  • 12 locations
Sertraline Combined With Fluvoxamine in the Treatment of Refractory Obsessive-compulsive Disorder

To verify that sertraline combined with fluvoxamine is superior to sertraline combined with aripiprazole

sertraline
paroxetine
fluvoxamine
antidepressants
fluoxetine
  • 0 views
  • 25 Jul, 2021
  • 1 location
Trial With the Treatment of Sertraline in Youth With Generalized, Separation and/or Social Anxiety Disorders. (EV-SoPRANO)

A Multicenter, acute, randomized, double-blind, placebo-controlled, flexible-dose trial with the treatment of sertraline.

Accepts healthy volunteers
social phobia
sertraline
psychosis
anxiety
  • 0 views
  • 24 Mar, 2022
  • 1 location
Investigating the Therapeutic Effects of Psilocybin in Treatment-Resistant Post-Traumatic

and sertraline. Psychedelic medications, including psilocybin, have recently received breakthrough designation by the US Food and Drug Administration (FDA) for other psychiatric indications

  • 0 views
  • 16 Sep, 2022
Specifying and Treating Anxiety in Autism Research (STAAR)

clinically significant anxiety by conducting a 16-week randomized comparative treatment trial of the Behavioral Intervention for Anxiety in Children with Autism (BIACA), the medication sertraline, and

pervasive developmental disorder
selective serotonin reuptake inhibitor
speech therapy
cognitive behavior therapy
medication regimen
  • 95 views
  • 22 Mar, 2022
  • 1 location
Partners in Caring for Anxious Youth

SSRI (either fluoxetine, sertraline, or escitalopram). CBT in PCAY will be 6 months in duration and include more family involvement, and more exposure opportunities than past trials. The 6-month acute

  • 0 views
  • 10 Sep, 2021
  • 3 locations