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Found 62 clinical trials
Fibro-inflammatory Progression From Acute to Chronic Pancreatitis

Observational prospective study evaluating the developement of chronic pancreatitis based on imaging modalities as well as biochemical markers of inflammation, fibrosis and oxidative stress.

chronic pancreatitis
acute pancreatitis
  • 04 Mar, 2022
  • 3 locations
Sensory Abnormalities in Post-surgical Peripheral Neuropathy

The concept of normality is a cornerstone in medical practice and research. As an example, in clinical chemistry, a laboratory value based on a patient plasma sample, exceeding the +/- 1.96 x standard deviation (SD) range, referenced from a normative material, is per definition outside the normal range (the reference …

Accepts healthy volunteers
body mass index
  • 24 Mar, 2022
  • 1 location
PG and PK of Oxycodone to Personalize Post-op Pain Management Following Surgery in Children

Each year, in the U.S. alone, >6 million children undergo painful surgery; up to 50% of them experience significant and serious side effects with opioids and inadequate pain relief. Though 60% of this inter-individual variability in responses results from genetic variations, there is an almost complete lack of understanding of …

postoperative pain
opioid dependence
pain relief
pain reliever
  • 24 Mar, 2022
  • 1 location
Gynecologic Extramammary Paget's Disease

In addition to evaluating treatment outcomes, tissue samples and swabs will be collected as part of this study to allow physicians to better understand Extramammary Paget's Disease (EMPD). The researchers also want to learn more about the microorganisms (microbiome) that live on or near the areas of skin affected by …

  • 14 Jul, 2022
  • 1 location
Musculoskeletal Pain in Long COVID (MUSLOC)

Long COVID is a new disease, with musculoskeletal pain being one of the common presenting symptoms. This longitudinal study will explore the long COVID musculoskeletal pain aetiology, pathophysiology, impact on function and quality of life, prognosis and its natural evolution.

  • 09 May, 2022
  • 1 location
Pediatric Gastroparesis Registry (PGpR)

The objective of the Pediatric Gastroparesis Registry is to create a national prospective registry of children and adolescents with gastroparesis and gastroparesis-like syndrome (symptoms of gastroparesis but normal gastric emptying).

abdominal pain
early satiety
gastric emptying study
  • 10 Mar, 2022
  • 3 locations
The Impact of Insomnia on Pain in HIV (HIPPI)

The overall objective of this application is to investigate the impact of insomnia on pain, physical functioning, and inflammation in people living with HIV. The two aims of this study to determine 1) whether insomnia promotes increased sensitivity and inflammatory reactivity to pain stimuli, and 2) if weekly fluctuations in …

HIV Vaccine
sleep disorder
antiretroviral agents
Accepts healthy volunteers
antiretroviral therapy
  • 06 Jun, 2022
  • 1 location
Biometric and Biological Data for Diagnosis and Therapy of Pain Patients

In order to meet the challenge of an unambiguous diagnosis and effective therapy of SFN or the prognosis of susceptibility to the development of SFN, this project aims to create a data basis on which software will be developed during the project. This software should later be able to combine …

  • 17 Apr, 2021
  • 1 location
Clinical Phenotypes in Persons With Hip Osteoarthritis and Prognostic Factors for Outcome After Total Hip Arthroplasty (HIPPROCLIPS)

This prospective longitudinal cohort study aims (1) to identify clinical phenotypes in persons with hip osteoarthritis and after total hip arthroplasty, and (2) to identify prognostic factors for outcomes after total hip arthroplasty.

joint reconstruction
joint arthroplasty
hip arthroplasty
  • 17 Mar, 2022
  • 1 location
The Predictive Value of Cervical Paraspinal Muscle Twitching During Motor Stimulation Testing on Cervical Facet Joint Radiofrequency Ablation Outcomes

The investigators aim to determine whether cervical paravertebral muscle twitching during motor testing as part of performing cervical RFAs is associated with a greater likelihood of treatment success, and greater magnitude or duration of analgesia. The investigators propose a straightforward grading scale based on visual and tactile information readily available …

  • 16 Oct, 2022
  • 1 location