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Found 62 clinical trials
The Back Pain Consortium Research Program Study (BACPAC)

This study is being completed to better understand who benefits from different chronic pain treatments and how these treatments work. This study will include a four week run-in period for all cLBP participants. After completing the PainGuide (online or smart phone accessible website) run-in period, participants will be assessed using …

  • 0 views
  • 05 Jul, 2022
  • 1 location
Pain Sensitivity and Psychological Profile of Chronic Low Back Pain Patients

This study aims to characterize pain sensitivity and psychological profile of CLBP patients in comparison with pain free adults, and explore their predictive role on hypnosis outcomes, an effective intervention for pain control.

low back pain
back pain
Accepts healthy volunteers
  • 0 views
  • 06 Jun, 2022
  • 1 location
Modulating Mechanisms in Patients With Chronic Subjective Tinnitus and/or Chronic Pain

This is a cross-sectional investigation into modulating mechanisms in patients with chronic subjective tinnitus, which will compare 4 patient groups namely chronic tinnitus with chronic pain, chronic tinnitus without chronic pain, chronic pain without tinnitus and healthy controls.

Accepts healthy volunteers
heat
insomnia
anxiety
pulsatile tinnitus
  • 3 views
  • 07 Oct, 2022
  • 1 location
Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics

To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV

Accepts healthy volunteers
  • 0 views
  • 09 Dec, 2021
  • 1 location
Explosive Synchronization of Brain Network Activity in Chronic Pain

This project is being conducted to evaluate the impact of explosive synchronization (ES) and its treatment with non-invasive brain stimulation in fibromyalgia (FM). The study design has three components, however, only 2 aims are enrolling participants. The first part (Aim1) is a cross sectional assessment of brain network explosive synchronization …

functional magnetic resonance imaging
Accepts healthy volunteers
chronic pain
  • 15 views
  • 15 Oct, 2022
  • 1 location
Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain.

The aim of this study is to evaluate the efficacy of anesthetic blocks repeated with bupivacaine in the management of patients with persistent dentoalveolar pain. Goals are to improve the understanding of the physiopathological mechanisms of persistent dentoalveolar pain and to highlight predictive criteria for the effectiveness of anesthetic blocks.

lidocaine
bupivacaine
  • 0 views
  • 25 Jan, 2021
  • 1 location
Long-term Pain Modulation by Intravenous Esketamine in CRPS (KetCRPS-2)

Intravenous administration of esketamine is an effective recognized therapeutic option in refractory pain in CRPS, which sometimes in at least a part of the patients has a prolonged therapeutic effect. Unfortunately, CRPS literature contains a wide range of ketamine dosing regimens with the result that clinical protocols on dosage and …

ketamine
  • 0 views
  • 06 Jun, 2022
  • 1 location
Home-based Transcranial Stimulation in the Treatment of Patients With Refractory Chronic Pain

Refractory chronic pain represents a serious and limiting health condition which does not respond to standard pharmacological therapy. Thus, it emerges the necessity of new techniques to treat these group of diseases, such as the transcranial electrical stimulation (tES). This procedure induces a low-intensity electrical current through the scalp to …

electrical stimulation
chronic pain
anxiety
cancer
  • 0 views
  • 03 Nov, 2021
  • 1 location
Closed-Loop Deep Brain Stimulation for Refractory Chronic Pain

Chronic pain affects 1 in 4 US adults, and many cases are resistant to almost any treatment. Deep brain stimulation (DBS) holds promise as a new option for patients suffering from treatment-resistant chronic pain, but traditional approaches target only brain regions involved in one aspect of the pain experience and …

postherpetic neuralgia
nerve crush
neuralgia
radiation plexopathy
spinal cord
  • 388 views
  • 15 Feb, 2022
  • 1 location
Neurosensorial Disorder and Pain in Oral Cavity and Oropharynx Cancer Traited Patients (OCAPA)

Following preliminary studies carried out in our department on these subject and subjective findings during clinical examinations, it has been shown that pain is a symptom that is rarely reported following treatment. Instead, neurosensory disorders such as hypoesthesia and paresthesia are found. The objective of the study is to map …

  • 0 views
  • 27 Jan, 2021
  • 1 location