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Found 60 clinical trials
Integrative Medicine in Pain Management in Sickle Cell Disease

The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupuncture analgesia in patients with sickle cell disease.

hydroxyurea
analgesia
pain relieving
chronic pain
oxycodone
  • 0 views
  • 25 Mar, 2022
  • 1 location
Study of Low-intensity Focused Ultrasound Effects on Heat Evoked fMRI Signals

resting and heat evoked brain signaling using a quantitative sensory testing device. Heart rate, blood pressure, respiratory rate, and skin moisture is monitored. Participants complete a battery of

Accepts healthy volunteers
heat
  • 0 views
  • 04 Oct, 2022
  • 1 location
Mind and Body Approaches to Pain Reduction in Youth With Migraine

study design of this mechanistic investigation includes functional magnetic resonance imaging (fMRI), daily headache diaries, assessment of conditioned pain modulation via quantitative sensory testing

chronic migraine
daily headaches
headache disorder
daily headache
cognitive therapy
  • 19 views
  • 24 Mar, 2022
  • 1 location
Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee

clinical assessments, blood draws, questionnaires, daily pain diaries, sensory testing, as well as have functional connectivity magnetic resonance imaging (fcMRI).

  • 0 views
  • 12 Oct, 2022
  • 1 location
EMG Biofeedback Treatment for Chronic Low Back Pain, Cancer Pain and Migraines (BEAT-Pain)

will be instructed on how to use the device by a trained biofeedback instructor. Patients in the control group will undergo sensory testing procedures at baseline and after treatment period but

back pain
episodic migraine
cancer
anxiety
headache
  • 10 views
  • 03 May, 2022
  • 1 location
Repeated Cannabis Administration on Experimental Pain and Abuse Liability

Test (CPT) and Quantitative Sensory Testing Thermal Temporal Summation (QST-TTS), and participants will smoke cannabis 3x/day. Throughout the study, experimental pain and abuse-related effects will be

opioid
chronic pain
Accepts healthy volunteers
hyperalgesia
  • 0 views
  • 07 Jul, 2022
  • 1 location
Impact of Repeatedly-Administered THC-cannabis on Experimental Pain and Abuse Liability in Humans

distinct modalities of experimental pain will be assessed: The Cold Pressor Test (CPT) and Quantitative Sensory Testing Thermal Temporal Summation (QST-TTS). Throughout the study, experimental pain and

opioid
chronic pain
Accepts healthy volunteers
hyperalgesia
  • 0 views
  • 07 Oct, 2022
  • 1 location
A Phase I Study of the Intrathecal Administration of Resiniferatoxin for Treating Severe Refractory Pain Associated With Advanced Cancer

> Vitals Blood draw, Urinalysis, neurological and sensory testing, EKG on days 7, 14 and 30 after the injection MRI scans of the head and back, Urology assessment and PEFR on day

catheter placement
analgesia
pain relieving
aspirin
neurological examinations
  • 338 views
  • 22 Oct, 2022
  • 1 location
Pancreatic Endotherapy for Refractory Chronic Pancreatitis (PERCePT)

The purpose of this study is to evaluate whether endoscopic ultrasound (EUS) only versus EUS + endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic endotherapy reduces pain in the treatment of chronic pancreatitis with pancreatic duct obstruction.

  • 6 views
  • 04 Oct, 2022
  • 2 locations
The Back Pain Consortium Research Program Study (BACPAC)

This study is being completed to better understand who benefits from different chronic pain treatments and how these treatments work. This study will include a four week run-in period for all cLBP participants. After completing the PainGuide (online or smart phone accessible website) run-in period, participants will be assessed using …

  • 0 views
  • 05 Jul, 2022
  • 1 location