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Found 61 clinical trials
MaST: MEG and Brain Stimulation in Tinnitus

unknown although maladaptive plasticity due to sensorineural hearing loss is thought to play a big role. Neuroimaging studies have pointed to over-activation or excessive spontaneous activity within the

anxiety
audiogram
transcranial direct current stimulation
depression
sleep disturbances
  • 3 views
  • 04 Aug, 2021
  • 1 location
Iowa Cochlear Implant Clinical Research Center Hybrid L24 and Standard Cochlear Implants in Profoundly Deaf Infants

The purpose of this feasibility study is to evaluate whether implantation of one Nucleus L24 electrode array and one FDA approved standard-length device in the contralateral ear can provide useful binaural hearing in pediatric subjects who have bilateral severe to profound hearing loss, meeting the criteria for cochlear implantation. Unlike …

  • 66 views
  • 25 Jan, 2021
  • 1 location
CT and MRI for Pre-Operative Cochlear Imaging

This study investigates the role of the preoperative computed tomography (CT) and magnetic resonance imaging (MRI) before cochlear implants and their role in selecting suitable patients for surgery.

cochlear implant
deafness
ct scan
  • 30 views
  • 24 Jan, 2021
  • 1 location
Study of Viral Transduction of Human Auditory Sensory Cells for the Development of Gene Therapy

Gene therapy is a promising strategy to treat hearing loss and vestibular disorders, and Associated adenovirus (AAV) is shown as a good viral vector for inner ear therapy in animal models. This study aims to study in vitro viral transduction of AAV in human inner ear cells, collected during non-conservative …

gene therapy
viral vector
deafness
  • 69 views
  • 26 Jan, 2021
  • 5 locations
Evaluation of an Open-source Speech-processing Platform

Determining acceptability and usability of a wearable open-source speech processing platform (Master Hearing Aid) developed for hearing-aid research

deafness
  • 22 views
  • 23 Jan, 2021
  • 1 location
AChild - Austrian Children With Hearing Impairment - Longitudinal Database

There is high variability in outcomes in children with hearing impairment. Existing literature focus mainly on subpopulations (children with hearing aids, children with CI) and is usually not epidemiological. Often children with additional needs (intellectual disability, visual impairment, autism spectrum disorder, complex syndromes) are excluded from the studies. This subgroup …

  • 0 views
  • 26 Feb, 2021
  • 1 location
Analysis of Clinical Profiles of Chinese Patients With Normal Tension Glaucoma

To obtain demographic and baseline ophthalmic parameters (such as Intraocular Pressure profiles, disc morphological characteristics, central corneal thickness, peripapillary retinal nerve fibre layer thickness and its serial changes, visual field changes, severity of any medical associations—e.g. hypertension, migraine, strokes, silent cerebral infarcts) with non-invasive measurements, in Chinese Patients with Normal …

tension
intraocular pressure
low tension glaucoma
hypertension
  • 30 views
  • 07 Nov, 2020
  • 1 location
The SeaSHeL National Prospective Cohort Study

investigation, and these cases are termed idiopathic 'sudden onset sensorineural hearing loss' (SSNHL). Treatment options for idiopathic SSNHL mainly include steroid treatments, with considerable limitations in

deafness
audiogram
hard of hearing
  • 20 views
  • 24 Jan, 2021
  • 1 location
Investigation of Anatomical Correlates of Speech Discrimination

Understanding speech is essential for good communication. Individuals with hearing loss and poor speech discrimination often have little success with hearing aids because amplifying sound improves audibility, but not clarity of the speech signal. The purpose of this study is to determine the relative importance of the sensory cells of …

fitting
AIDS
hard of hearing
fit hearing aid
audiogram
  • 220 views
  • 17 Jun, 2021
  • 1 location
Natural History of Autosomal Dominant Hearing Loss

Background Hereditary hearing loss is one of the most common sensory disabilities affecting newborns. The main options for people with hereditary hearing loss are hearing aids and cochlear implants. Both options have their limitations and do not restore biological hearing. Researchers want to learn if gene editing might be a …

cochlear implant
AIDS
vertigo
hard of hearing
audiogram
  • 17 views
  • 10 Jun, 2021
  • 1 location