Found 12 clinical trials
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Currently Recruiting
Therapeutic Strategy Guided by PET-TDM for Patients With Seminoma
) or metastatic (cohort 2) seminoma
- 1 views
- 08 Nov, 2020
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Phase 2 trial
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Accepting pediatric ages
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Accepting Seniors
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10s of participants
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An interventional trial
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For males only
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Currently Recruiting
Trial to Evaluate Progression Free Survival With Primary Retroperitoneal Lymph-node Dissection (pRPLND) Only in Patients With Seminomatous Testicular Germ Cell Tumors With Clinical Stage IIA/B (PRIMETEST)
Primary objective: to evaluate progression-free survival in patients with clinical stage II A/B seminomatous germ cell tumor undergoing primary retroperitoneal lymph node dissection (RPLND) without adjuvant treatment Secondary objectives: overall survival perioperative complications (Clavien-Dindo score) quality of life (EORTC QLQ C30, EORTC QLQ TC26) long term sequelae rate of retrograde …
- 3 views
- 08 Nov, 2020
- 1 location
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Nivolumab in Platinum Recurrent or Refractory Metastatic Germ Cell Tumors
To assess the clinical activity of nivolumab monotherapy, as measured by the investigator-assessed clinical benefit rate (CBR), in patients with platinum-recurrent or platinum-refractory metastatic germ cell tumors (GCT). CBR is defined by sum of complete responses (CR), partial responses (PR) and stable disease (SD) for at least 3 months, with …
- 19 views
- 08 Nov, 2020
- 1 location
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For males only
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Endocrinology
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Currently Recruiting
Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors
This randomized phase III trial studies how well standard-dose combination chemotherapy works compared to high-dose combination chemotherapy and stem cell transplant in treating patients with germ cell tumors that have returned after a period of improvement or did not respond to treatment. Drugs used in chemotherapy, such as paclitaxel, ifosfamide, …
- 803 views
- 17 Jan, 2021
- 93 locations
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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100s of participants
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An interventional trial
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For males only
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Currently Recruiting
Magnetic Resonance Imaging and Computed Tomography in Patients With Stage I Seminoma of the Testicle
. PURPOSE: This randomized phase III trial is comparing four different MRI and CT scan schedules in patients with stage I seminoma of the testicle.
- 717 views
- 07 Nov, 2020
- 12 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For all genders
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Endocrinology
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Currently Recruiting
Nivolumab and Ipilimumab in Treating Patients With Rare Tumors
>Transitional cell carcinoma other than that of the renal, pelvis, ureter, or bladder (closed to accrual) Cell tumor of the testes and extragonadal germ tumors: A) Seminoma and testicular
- 5957 views
- 17 Jan, 2021
- 793 locations
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Multi-country trial
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Phase 3 trial
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Accepting pediatric ages
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Accepting Seniors
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1000s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Active Surveillance Bleomycin Carboplatin Etoposide or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors
This phase III trial studies how well active surveillance, bleomycin, carboplatin, etoposide, or cisplatin work in treating pediatric and adult patients with germ cell tumors. Active surveillance may help doctors to monitor subjects with low risk germ cell tumors after their tumor is removed. Drugs used in chemotherapy, such as …
- 341 views
- 27 Dec, 2020
- 343 locations
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Multi-country trial
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Nephrology
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Currently Recruiting
Reduced Intensity Radio-chemotherapy for Stage IIA/B Seminoma
The trial investigates a stage-adapted (stage IIA or IIB) de-escalation of the standard treatments in the context of a multimodality treatment with chemo- and radiotherapy in seminoma patients
- 14 views
- 21 Dec, 2020
- 16 locations
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Phase 2 trial
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Accepting Seniors
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Accepting adults
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10s of participants
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An interventional trial
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For all genders
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Family Medicine
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Currently Recruiting
Evaluating Immune Therapy Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors
The purpose of this study is to test the safety and effectiveness of durvalumab with tremelimumab in patients with relapsed or refractory germ cell tumors.
- 26 views
- 27 Nov, 2020
- 7 locations
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Phase 3 trial
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Accepting adults
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100s of participants
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An interventional trial
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For males only
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Nephrology
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Currently Recruiting
Adjuvant Bleomycin Etoposide and Cisplatin (BEP) Versus Carboplatin in Stage I Seminomatous Testicular Cancer
One course of adjuvant carboplatin AUC7 is considered internationally to be a standard treatment option in clinical stage I seminoma, regardless of risk factors. Treatment is based on a large
- 15 views
- 11 Nov, 2020
- 1 location
- 1
- 2